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LYZ protein :: Lysozyme Protein

Scan QR to view Datasheet Catalog #    MBS173158 LYZ protein
Unit / Price
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 Product Name   

Lysozyme (LYZ), Protein

★Popular Item★
 Also Known As   

Lysozyme, Human Neutrophils

 Product Synonym Names    Lysozyme, Human Neutrophils - >=95% (SDS-PAGE)
 Product Gene Name   

LYZ protein

[Similar Products]
 Product Synonym Gene Name    LZM [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Purity/Purification    >= 95% (SDS-PAGE)
 Form/Format    Liquid
Appearance: Clear, colorless solution
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 Source    Human Neutrophils
 EC Number
 Recertification    1 year
 Protein    1.0 - 3.0 mg protein/mL (A280 E=2.5)
 CAS Number    900-63-2
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 Preparation and Storage    At -20 degree C
 Other Notes    Small volumes of LYZ protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for LYZ protein

   Custom preparations, technical support, bulk quantities and aliquoting available.

Human Lysozyme is an enzyme commonly referred to as the "body's own antibiotic" since it kills bacteria. Human Lysozyme is a an enzyme that destroys bacterial cell walls by hydrolyzing the polysaccharide component of the cell wall. Human Lysozyme is abundantly present in a number of secretions, such as tears. Human Lysozyme is present in cytoplasmic granules of the polymorphonuclear neutrophils (PMN) and released through the mucosal secretions (such as tears and saliva).

Clinical significance: Human Lysozyme levels in the blood are often increased in sarcoidosis.

Lysozyme protects against bacterial infection by breaking down the carbohydrates in bacterial cell walls, killing them. Hence, lysozyme is part of the innate immune response. In saliva it protects the oral cavity from pathogens. In times of increased inflammation, such as during inflammation of the salivary glands or after a tonsillectomy, there is an increase in lysozyme. This protein also works in synergy with the bactericidal properties of lactoferrin, another common protein found in mucosal secretions.

Lysozyme also has fungicidal properties, protecting mucosal areas from invasion by pathogenic yeast or fungi. Lysozyme has been shown to inhibit viral replication and infection such HIV. Lysozyme also interacts with and increases the function of histatin, a protein shown to be bactericidal and fungicidal.
 Product Categories/Family for LYZ protein    Proteins; Antigens; Standards/controls; Native Proteins; Lysozyme
NCBI/Uniprot data below describe general gene information for LYZ. It may not necessarily be applicable to this product.
 NCBI GI #    112984208
 NCBI GeneID    693015
 NCBI Accession #    NP_001037448.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001043983.1 [Other Products]
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 UniProt Secondary Accession #    Q9TWL7 [Other Products]
 UniProt Related Accession #    P48816 [Other Products]
 Molecular Weight    ~14,700
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 NCBI Official Full Name    lysozyme
 NCBI Official Symbol    Lzm [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    lysozyme; 1,4-beta-N-acetylmuramidase
 UniProt Protein Name    Lysozyme
 UniProt Synonym Protein Names   
 Protein Family    Lysozyme
 UniProt Entry Name    LYS_BOMMO
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 UniProt Comments for LYZ    Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Active against E.coli and M.luteus.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with LYZ protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >61 publications with LYZ and Blood
 Brain Antibodies  >10 publications with LYZ and Brain
 Embryonic Tissue Antibodies  >2 publications with LYZ and Embryonic Tissue
 Midgut Antibodies  >1 publications with LYZ and Midgut
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