Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Protein rightarrow PKC-delta  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Alpha-1 Acid Glycoprotein (A1GP) Protein
 • AHRR Antibody
 • CU070 (FAM207A) Antibody
 • urotensin  II (UII) ELISA Kit
 • Mannonate dehydratase (uxuA) Recombinant Protein
 • A disintegrin and metalloproteinase with thrombospondin moti... Recombinant Protein
 • EIF4E Antibody
 • Caspase-3 (CASP3) Antibody
 • Unphosphorylated Dok1 (Tyr-362) Peptide Peptide
 • EL (Endothelial lipase) CLIA Kit
 • Osteocalcin (BGLAP) Native Protein
 • M1 (A- Vietnam-1203-2004)(H5N1) Antibody
 • Tyrosine Phosphatase Non Receptor Type-6 (PTPN6) Recombinant Protein
 • Histone H4 (HIST4H4) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

PKC-delta protein

Scan QR to view Datasheet Catalog #    MBS483014 PKC-delta protein
Unit / Price
0.001 mg  /  $220 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PKC-delta, Protein

★Popular Item★
 Also Known As   

PKC-delta Standard

 Product Synonym Names    Protein Kinase C Delta Standard
 Product Gene Name   

PKC-delta protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    176977
 3D Structure    ModBase 3D Structure for Q05655
Section Bar
Section Bar
 Concentration    20 mug/mL (lot specific)
Section Bar
 Contents    1.0 mug of protein in 50 muL.
 Enzyme Activity    Not enzymatically active
Section Bar
 Preparation and Storage    Stable indefinitely at At -70 degree C. or at least one year at -20 degree C.
 Other Notes    Small volumes of PKC-delta protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for PKC-delta protein

   Description: Human recombinant kinase Cd expressed in baculoviral insect expression system. The protein is suspended in SDS/mercaptoethanol sample buffer with a bromphenol blue dye marker.
 Applications Tested/Suitable for PKC-delta protein   

Western Blot (WB)

 Application Notes for PKC-delta protein    Intended for use as a standard for Western blots using enhanced chemiluminescence. For blots using less sensitive substrates, such as alkaline phosphatase, larger amounts of protein should be loaded onto the gel. Load 2 - 5 muL of standard directly from vial. No dilution is necessary.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PKC-delta. It may not necessarily be applicable to this product.
 NCBI GI #    47157325
 NCBI GeneID    5580
 NCBI Accession #    NP_997704.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_212539.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q05655 [Other Products]
 UniProt Secondary Accession #    Q15144; Q86XJ6; B0KZ81; B2R834 [Other Products]
 UniProt Related Accession #    Q05655 [Other Products]
 Molecular Weight    80,953 Da
Table BarTOPTable Bar
 NCBI Official Full Name    protein kinase C delta type
 NCBI Official Synonym Full Names    protein kinase C, delta
 NCBI Official Symbol    PRKCD [Similar Products]
 NCBI Official Synonym Symbols   
MAY1; PKCD; ALPS3; CVID9; nPKC-delta
[Similar Products]
 NCBI Protein Information    protein kinase C delta type; protein kinase C delta VIII; tyrosine-protein kinase PRKCD
 UniProt Protein Name    Protein kinase C delta type
 UniProt Synonym Protein Names   
Tyrosine-protein kinase PRKCD (EC:2.7.10.2); nPKC-delta
 UniProt Gene Name    PRKCD [Similar Products]
 UniProt Synonym Gene Names    SDK1 [Similar Products]
 UniProt Entry Name    KPCD_HUMAN
Section Bar
 NCBI Summary for PKC-delta    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for PKC-delta    PKCD: an AGC kinase of the PKC family. A novel PKC: Ca2 independent but still regulated by PS, DAG and phorbol esters. Caspase-3 appears to liberate a sphingosine-activated catalytic fragment that has altered regulatory mechanisms and substrate specificities.

Protein type: Protein kinase, AGC; Nuclear receptor co-regulator; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Tumor suppressor; EC 2.7.11.13; AGC group; PKC family; Delta subfamily

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: nucleoplasm; nuclear matrix; mitochondrion; perinuclear region of cytoplasm; endoplasmic reticulum; cytoplasm; plasma membrane; intercellular junction; nucleus; cytosol

Molecular Function: calcium-independent protein kinase C activity; protein serine/threonine kinase activity; protein binding; protein kinase C activity; enzyme binding; metal ion binding; insulin receptor substrate binding; enzyme activator activity; non-membrane spanning protein tyrosine kinase activity; ATP binding

Biological Process: B cell proliferation; negative regulation of MAP kinase activity; interleukin-12 production; peptidyl-tyrosine phosphorylation; nerve growth factor receptor signaling pathway; apoptosis; negative regulation of insulin receptor signaling pathway; signal transduction; protein amino acid phosphorylation; positive regulation of protein amino acid dephosphorylation; negative regulation of filopodium formation; positive regulation of superoxide release; regulation of receptor activity; negative regulation of protein binding; cell structure disassembly during apoptosis; epidermal growth factor receptor signaling pathway; platelet activation; negative regulation of peptidyl-tyrosine phosphorylation; fibroblast growth factor receptor signaling pathway; neutrophil activation; protein stabilization; negative regulation of actin filament polymerization; cytokine and chemokine mediated signaling pathway; peptidyl-threonine phosphorylation; cell cycle; phospholipase C activation; negative regulation of inflammatory response; defense response to bacterium; interleukin-10 production; innate immune response; gene expression; immunoglobulin mediated immune response; vascular endothelial growth factor receptor signaling pathway; blood coagulation; induction of apoptosis by oxidative stress

Disease: Autoimmune Lymphoproliferative Syndrome, Type Iii
Table BarTOPTable Bar
 Research Articles on PKC-delta    1. Docking and physicochemical studies indicated that BTK was involved in close contact with Tyr86 and Tyr106 of MAL, whereas PKCdelta may phosphorylate Tyr106 only.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with PKC-delta proteinPathways associated with PKC-delta protein
 Reference Product  PubMed Publications
 SRC protein  >64 publications with PKC-delta and SRC
 MAPK1 protein  >36 publications with PKC-delta and MAPK1
 MAPK3 protein  >35 publications with PKC-delta and MAPK3
 STAT1 protein  >10 publications with PKC-delta and STAT1
 RHOA protein  >9 publications with PKC-delta and RHOA
 PRKCQ protein  >8 publications with PKC-delta and PRKCQ
 STAT3 protein  >8 publications with PKC-delta and STAT3
 FYN protein  >7 publications with PKC-delta and FYN
 IRS1 protein  >6 publications with PKC-delta and IRS1
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 C-type Lectin Receptors (CLRs) Pathway antibodies  C-type Lectin Receptors (CLRs) Pathway Diagram
 CLEC7A (Dectin-1) Signaling Pathway antibodies  CLEC7A (Dectin-1) Signaling Pathway Diagram
Diseases associated with PKC-delta proteinOrgans/Tissues associated with PKC-delta protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >50 publications with PKC-delta and Necrosis
 Heart Diseases Antibodies  >48 publications with PKC-delta and Heart Diseases
 Nervous System Diseases Antibodies  >39 publications with PKC-delta and Nervous System Diseases
 Disease Models, Animal Antibodies  >36 publications with PKC-delta and Disease Models, Animal
 Inflammation Antibodies  >35 publications with PKC-delta and Inflammation
 Hypertrophy Antibodies  >23 publications with PKC-delta and Hypertrophy
 Breast Neoplasms Antibodies  >21 publications with PKC-delta and Breast Neoplasms
 Adenocarcinoma Antibodies  >19 publications with PKC-delta and Adenocarcinoma
 Cardiomyopathies Antibodies  >17 publications with PKC-delta and Cardiomyopathies
 Intestinal Neoplasms Antibodies  >16 publications with PKC-delta and Intestinal Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >144 publications with PKC-delta and Blood
 Heart Antibodies  >92 publications with PKC-delta and Heart
 Vascular Antibodies  >78 publications with PKC-delta and Vascular
 Brain Antibodies  >69 publications with PKC-delta and Brain
 Nerve Antibodies  >38 publications with PKC-delta and Nerve
 Kidney Antibodies  >34 publications with PKC-delta and Kidney
 Liver Antibodies  >31 publications with PKC-delta and Liver
 Lung Antibodies  >30 publications with PKC-delta and Lung
 Skin Antibodies  >28 publications with PKC-delta and Skin
 Bone Antibodies  >23 publications with PKC-delta and Bone
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions