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thrombin protein

Scan QR to view Datasheet Catalog #    MBS173189 thrombin protein
Unit / Price
25000 Units  /  $200 +1 FREE 8GB USB
100000 Units  /  $345 +1 FREE 8GB USB
500000 Units  /  $870 +1 FREE 8GB USB
 
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 Product Name   

Thrombin, Protein

★Popular Item★
 Also Known As   

Thrombin, Bovine Plasma

 Product Synonym Names    Thrombin, Bovine - Standard Grade
 Product Gene Name   

thrombin protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Purity/Purification    Partially Purified
 Form/Format    Lyophilized
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 Source    Bovine Plasma
 EC Number    3.4.21.5
 Specific Activity    > 100 US U/mg protein
 Reconstitution    0.9% NaCl
 Recertification    3 years
 Protein    > 0.4 mg protein/mg (Biuret)
 pH    ~7.0
 Loss on Drying    < 5.0%
 CAS Number    2594047
 Activity    50,000 - 150,000 US U/gram
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 Preparation and Storage    At -20 degree C
 Other Notes    Small volumes of thrombin protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for thrombin purchase    By acting as a serine protease enzyme, thrombin converts the soluble protein fibrinogen into a matrix forming insoluble complexed clotting and coagulation factor, fibrin. Thrombin is derived from protease cleavage of prothrombin, through vitamin K and calcium binding dependent factors. Inhibition of these amino acids removal in blood by thrombin inhibitors of the thrombin active site results in loss of ability to clot or to activate platelet receptor proteins required for aggregation. Cell research into active site thrombin complex structure, discovery of potential new thrombin inhibitor complex or understanding its crystal structure and crystallographic structure thrombin complex, further require a purified source of thrombin. A purified bovine thrombin, with activities ranging from 50,000 - 150,000 US U/gram. is available as an economical Standard grade lyophilized protein for multiple research laboratory protocols, such as defibrinate human alpha fibrinogen from plasma or removal of affinity tags.
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Related Product Information for thrombin protein

   MyBioSource producer and supplier of bovine Thrombin, medical research of proteolytic enzymes and manufacturing of defibrinating human plasma and serum free media component.

Custom preparations, technical support, bulk quantities and aliquoting available.

Bovine Thrombin EC 3.4.21.5 (activated Factor II) is a coagulation protein that has many effects in the coagulation cascade. Bovine Thrombin is a serine protease that converts fibrinogen into fibrin.

Bovine Thrombin used as a reagent, Thrombin has proven useful in the laboratory evaluation of many fibrinogen(s)

Our customers use Bovine Thrombin to defibrinate human plasma, producing serum matrixes to be used as controls and standards. Bovine Thrombin High specific material available (> 2000 U/mg protein) is used to cleave r-fusion proteins containing a thrombin site for removal of affinity tags as well as certain diagnostic pharmaceutical applications.

Thrombin promotes chemotaxis in monocytes, neurite retraction in neuron Thrombin serves as a potent mitogenic agent in fibroblast growth and functions as a serum-free media component for several cell lines

Bovine Thrombin is a multifunctional proteolytic enzyme which acts both specifically and non-specifically with several proteins, cells, surfaces, and other molecules. Bovine Thrombin(s) essential role in the clotting process has been well characterized where it converts fibrinogen, a soluble plasma glycoprotein, to an insoluble protein gel called fibrin, the essential component of the blood clot.
 Product Categories/Family for thrombin protein    Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Thrombin
NCBI/Uniprot data below describe general gene information for thrombin. It may not necessarily be applicable to this product.
 NCBI GI #    213487
 NCBI Accession #    AAA49433.1 [Other Products]
 Molecular Weight    36000 [Similar Products]
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 NCBI Official Full Name    thrombin, partial
 UniProt Protein Name    Thrombin
 UniProt Synonym Protein Names   
Thrombin
 Protein Family    Thrombin
 UniProt Gene Name    thrombin [Similar Products]
 UniProt Entry Name    Q91218_ONCMY
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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