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cTnT protein :: Troponin T Cardiac Protein

Scan QR to view Datasheet Catalog #    MBS664015 cTnT protein
Unit / Price
0.1 mg  /  $1,940 +2 FREE 8GB USB
0.5 mg  /  $3,730 +4 FREE 8GB USB
1 mg  /  $5,285 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Troponin T Cardiac (cTnT), Protein

 Also Known As   

Rabbit cardiac troponin T (cTnT)

 Product Gene Name   

cTnT protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Form/Format    Lyophilized from 0.01 M HCl.
Product is recommended to reconstitute with urea/Tris buffer, pH 7.5 (7 M urea, 5 mM EDTA, 15 mM mercaptoethanol, 20 mM Tris).
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 Source Note    Rabbit heart tissue.
 Analysis    Purity > 98 % (SDS-PAGE).
Immunological identity confirmed by reaction with monoclonal antibody that is specific for the TnT cardiac isoform.
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 Preparation and Storage    At -20 degree C (-70 degree C for long term storage)
 Other Notes    Small volumes of cTnT protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for cTnT. It may not necessarily be applicable to this product.
 NCBI GI #    6981666
 NCBI GeneID    24837
 NCBI Accession #    NP_036808.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012676.1 [Other Products]
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 UniProt Related Accession #    P50753 [Other Products]
 Molecular Weight    34,452 Da
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 NCBI Official Full Name    troponin T, cardiac muscle
 NCBI Official Synonym Full Names    troponin T type 2 (cardiac)
 NCBI Official Symbol    Tnnt2 [Similar Products]
 NCBI Official Synonym Symbols   
Ctt; CTTG; Tnnt3; RATCTTG
[Similar Products]
 NCBI Protein Information    troponin T, cardiac muscle; cTnT; tnTc; Troponin T cardiac; cardiac troponin T2; troponin T2, cardiac; cardiac muscle troponin T
 UniProt Protein Name    Troponin T, cardiac muscle
 UniProt Synonym Protein Names   
Cardiac muscle troponin T; cTnT
 UniProt Gene Name    Tnnt2 [Similar Products]
 UniProt Synonym Gene Names    TnTc; cTnT [Similar Products]
 UniProt Entry Name    TNNT2_RAT
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 NCBI Summary for cTnT    tropomyosin-binding subunit of troponin; confers calcium-sensitivy to actinomysin ATPase activity in striated muscle [RGD, Feb 2006]
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 UniProt Comments for cTnT    TNNT2: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart. Belongs to the troponin T family. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: Motor; Motility/polarity/chemotaxis

Cellular Component: sarcomere; troponin complex; myofibril; cytoplasm; striated muscle thin filament

Molecular Function: protein binding, bridging; troponin C binding; structural constituent of cytoskeleton; troponin I binding; ATPase activity; tropomyosin binding; actin binding

Biological Process: actin crosslink formation; protein heterooligomerization; atrial cardiac muscle morphogenesis; metabolic process; regulation of muscle contraction; heart development; regulation of muscle filament sliding speed; sarcomere organization; regulation of heart contraction; muscle filament sliding; muscle contraction; positive regulation of ATPase activity; ventricular cardiac muscle morphogenesis; response to calcium ion; negative regulation of ATPase activity; cardiac muscle contraction
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 Research Articles on cTnT    1. Replacement of the functionally corresponding N-terminal end portion of rat fast skeletal cardiac muscle (RfsTnT) into cardiac muscle troponin T (RcTnT), the observed functional differences associate with a sequence variation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with cTnT proteinDiseases associated with cTnT protein
 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >162 publications with cTnT and Cardiovascular Diseases
 Heart Diseases Antibodies  >158 publications with cTnT and Heart Diseases
 Cardiomyopathies Antibodies  >120 publications with cTnT and Cardiomyopathies
 Cardiomyopathy, Hypertrophic Antibodies  >102 publications with cTnT and Cardiomyopathy, Hypertrophic
 Cardiomyopathy, Hypertrophic, Familial Antibodies  >49 publications with cTnT and Cardiomyopathy, Hypertrophic, Familial
 Cardiomyopathy, Dilated Antibodies  >46 publications with cTnT and Cardiomyopathy, Dilated
 Cardiomegaly Antibodies  >41 publications with cTnT and Cardiomegaly
 Hypertrophy Antibodies  >38 publications with cTnT and Hypertrophy
 Heart Failure Antibodies  >36 publications with cTnT and Heart Failure
 Death, Sudden, Cardiac Antibodies  >34 publications with cTnT and Death, Sudden, Cardiac
Organs/Tissues associated with cTnT protein
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >124 publications with cTnT and Heart
 Embryonic Tissue Antibodies  >16 publications with cTnT and Embryonic Tissue
 Lung Antibodies  >5 publications with cTnT and Lung
 Prostate Antibodies  >2 publications with cTnT and Prostate
 Connective Tissue Antibodies  >2 publications with cTnT and Connective Tissue
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