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LOC541688 protein :: Trypsin Inhibitor, Corn Protein

Scan QR to view Datasheet Catalog #    MBS634314 LOC541688 protein
Unit / Price
1 mg  /  $390 +1 FREE 8GB USB
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 Product Name   

Trypsin Inhibitor, Corn (LOC541688), Protein

 Also Known As   

Trypsin Inhibitor, Corn (CTI)

 Product Gene Name   

LOC541688 protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Host    Corn kernels
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 Purity/Purification    Highly Purified
CTI is purified using a combination of published procedures (3,4). CTI is extracted from the kernels of fresh sweet corn into a physiologic buffer. The extract is de-fatted using acetone. The protein is further purified by employing gel
 Form/Format    Supplied as a liquid in 20mM Tris, 0.3M sodium chloride, pH 7.4.
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 Specific Activity    ~25 Units/mg
 Extinction Coefficient    20.0
[E1%1cm, 280nm was determined by ultracentrifugation studies (3)].
 Unit Definition    Preparations of CTI are tested for the ability to prolong the aPTT assay without affecting the PT assay. One unit is defined as the amount of CTI required to double the aPTT of 1ml normal human plasma.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C/-80 degree C. Aliquots are stable for at least 6 months at -20 degree C/-80 degree C.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of LOC541688 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for LOC541688 protein

   Corn Trypsin Inhibitor (CTI) is a small protein that is localized in the kernels of most species of corn. CTI is not only an inhibitor of trypsin, it is also a specific inhibitor of human Factor XIIa when tested in blood clotting experiments (1-6). The inhibitor forms a one-to-one complex with either trypsin or Factor XIIa. When added to plasma, it prolongs the activated partial thromboplastin time without affecting the PT assay (6). The specificity for Factor XIIa makes the inhibitor useful for the segregation and study of coagulation reactions (6).

The protein is a single chain molecule comprised of 112 amino acids (3,7). This yields a calculated molecular weight of 12,028D (7). The calculated molecular weight and that which has been determined by sedimentation equilibrium analyses of the purified protein (12,500D) are in good agreement (3). A comparison of the amino acid sequence of CTI to that of other trypsin or serine protease inhibitors reveals little or no similarities (7).
 Product Categories/Family for LOC541688 protein    Molecular Biology; MB-Coagulation Factors
NCBI/Uniprot data below describe general gene information for LOC541688. It may not necessarily be applicable to this product.
 NCBI GI #    162460894
 NCBI GeneID    541688
 NCBI Accession #    NP_001104908.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001111438.1 [Other Products]
 Molecular Weight    12,500 [Similar Products]
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 NCBI Official Full Name    trypsin inhibitor
 NCBI Official Symbol    LOC541688 [Similar Products]
 NCBI Protein Information    trypsin inhibitor
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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