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IGHA1 purified protein :: IgA Purified Protein

Scan QR to view Datasheet Catalog #    MBS230288 IGHA1 purified protein
Unit / Price
0.5 mg  /  $430 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IgA (IGHA1), Purified Protein

★Popular Item★
 Also Known As   

PURIFIED HUMAN SECRETORY IgA

 Product Gene Name   

IGHA1 purified protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    146900
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 Form/Format    Purified
Purified IgA - liquid
 Concentration    Approximate Protein Concentration: 1.0 mg/ml (lot specific)
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 Preparation    Purified human secretory IgA prepared by size-exclusion and ion exchange chromatography.
 Buffer Solution    Phosphate buffered saline
 Target Species    Human
 Preservative Stabilisers    None Present
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 Preparation and Storage    Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of IGHA1 purified protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IGHA1 purified protein

   Purified Human Secretory IgA is derived from human colostrum and is predominately in dimeric form, the monomers being linked by immunoglobulin J chain.
 Applications Tested/Suitable for IGHA1 purified protein   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for IGHA1. It may not necessarily be applicable to this product.
 NCBI GI #    113584
 NCBI GeneID    3493
 NCBI Accession #    P01876.2 [Other Products]
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 UniProt Related Accession #    P01876 [Other Products]
 Molecular Weight    37,655 Da [Similar Products]
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 NCBI Official Full Name    Ig alpha-1 chain C region, partial
 NCBI Official Synonym Full Names    immunoglobulin heavy constant alpha 1
 NCBI Official Symbol    IGHA1 [Similar Products]
 NCBI Official Synonym Symbols   
IgA1
[Similar Products]
 UniProt Protein Name    Ig alpha-1 chain C region
 Protein Family    IgA receptor
 UniProt Gene Name    IGHA1 [Similar Products]
 UniProt Entry Name    IGHA1_HUMAN
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 UniProt Comments for IGHA1    IGHA1: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.

Protein type: Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: extracellular space; extracellular region

Molecular Function: antigen binding

Biological Process: retinal homeostasis; receptor-mediated endocytosis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage
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 Research Articles on IGHA1    1. The heritability of IgA levels is moderate and can partly be attributable to common variation in the CD30L locus.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IGHA1 purified proteinOrgans/Tissues associated with IGHA1 purified protein
 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Inflammatory Response Pathway antibodies  Inflammatory Response Pathway Diagram
 Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies  Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with IGHA1 and Blood
 Brain Antibodies  >1 publications with IGHA1 and Brain
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