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NPY purified protein :: NEUROPEPTIDE Y Purified Protein

Scan QR to view Datasheet Catalog #    MBS230202 NPY purified protein
Unit / Price
0.1 mg  /  $250 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NEUROPEPTIDE Y (NPY), Purified Protein

 Also Known As   

SYNTHETIC HUMAN NEUROPEPTIDE Y

 Product Gene Name   

NPY purified protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    Y-P-S-K-P- D-N-P-G-E- D-A-P-A-E- D-M-A-R-Y- Y-S-A-L-R- H-Y-I-N-L- I-T-R-Q-R- Y-NH2
 OMIM    162640
 3D Structure    ModBase 3D Structure for P01303
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 Purity/Purification    HPLC: >97%
 Form/Format    Purified
Purified synthetic peptide - liquid
 Concentration    Total protein concentration 1.0mg/ml (lot specific)
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 Preparation    Synthetic peptide prepared by solid phase synthesis
 Target Species    Human
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 Preparation and Storage    Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of NPY purified protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for NPY purified protein   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for NPY. It may not necessarily be applicable to this product.
 NCBI GI #    4505449
 NCBI GeneID    4852
 NCBI Accession #    NP_000896.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000905.3 [Other Products]
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 UniProt Primary Accession #    P01303 [Other Products]
 UniProt Related Accession #    P01303 [Other Products]
 Molecular Weight    4271.8 amu [Similar Products]
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 NCBI Official Full Name    pro-neuropeptide Y preproprotein
 NCBI Official Synonym Full Names    neuropeptide Y
 NCBI Official Symbol    NPY [Similar Products]
 NCBI Official Synonym Symbols   
PYY4
[Similar Products]
 NCBI Protein Information    pro-neuropeptide Y; prepro-neuropeptide Y
 UniProt Protein Name    Pro-neuropeptide Y
 UniProt Synonym Protein Names   
Neuropeptide tyrosine; NPY
 Protein Family    Neuropeptide
 UniProt Gene Name    NPY [Similar Products]
 UniProt Synonym Gene Names    NPY; CPON [Similar Products]
 UniProt Entry Name    NPY_HUMAN
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 NCBI Summary for NPY    This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
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 UniProt Comments for NPY    NPY: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. Belongs to the NPY family.

Protein type: Secreted, signal peptide; Secreted; Hormone

Chromosomal Location of Human Ortholog: 7p15.1

Cellular Component: Golgi apparatus; extracellular space; cell; extracellular region

Molecular Function: G-protein coupled receptor activity; neuropeptide hormone activity; neuropeptide Y receptor binding; calcium channel regulator activity; receptor binding

Biological Process: blood circulation; behavior; adult feeding behavior; synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; cell proliferation; neuropeptide signaling pathway; calcium ion transport; regulation of blood pressure; positive regulation of appetite; digestion; regulation of appetite; feeding behavior; cerebral cortex development; cell motility; neurite development; central nervous system neuron development
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 Research Articles on NPY    1. Study demonstrated an interaction of NPY genotype and childhood emotional maltreatment on amygdala and posterior cingulate cortex activation during processing of emotional faces, in addition to a faster behavioral response
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NPY purified proteinPathways associated with NPY purified protein
 Reference Product  PubMed Publications
 POMC purified protein  >799 publications with NPY and POMC
 GAL purified protein  >208 publications with NPY and GAL
 CRH purified protein  >182 publications with NPY and CRH
 NPY1R purified protein  >59 publications with NPY and NPY1R
 SST purified protein  >35 publications with NPY and SST
 LEP purified protein  >22 publications with NPY and LEP
 NPY2R purified protein  >18 publications with NPY and NPY2R
 NPY5R purified protein  >14 publications with NPY and NPY5R
 GHRL purified protein  >12 publications with NPY and GHRL
 PPYR1 purified protein  >1 publications with NPY and PPYR1
 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Endothelin Pathway antibodies  Endothelin Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
Diseases associated with NPY purified proteinOrgans/Tissues associated with NPY purified protein
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >408 publications with NPY and Brain Diseases
 Cardiovascular Diseases Antibodies  >369 publications with NPY and Cardiovascular Diseases
 Hypertension Antibodies  >247 publications with NPY and Hypertension
 Anorexia Antibodies  >219 publications with NPY and Anorexia
 Pain Antibodies  >206 publications with NPY and Pain
 Epilepsy Antibodies  >205 publications with NPY and Epilepsy
 Inflammation Antibodies  >203 publications with NPY and Inflammation
 Seizures Antibodies  >175 publications with NPY and Seizures
 Substance-Related Disorders Antibodies  >139 publications with NPY and Substance-Related Disorders
 Heart Diseases Antibodies  >132 publications with NPY and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4490 publications with NPY and Brain
 Nerve Antibodies  >2233 publications with NPY and Nerve
 Muscle Antibodies  >879 publications with NPY and Muscle
 Pancreas Antibodies  >191 publications with NPY and Pancreas
 Uterus Antibodies  >63 publications with NPY and Uterus
 Prostate Antibodies  >56 publications with NPY and Prostate
 Placenta Antibodies  >22 publications with NPY and Placenta
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