NP_002104.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,651 Da
NCBI Official Full Name
complement factor H-related protein 1
NCBI Official Synonym Full Names
complement factor H related 1
NCBI Official Synonym Symbols
CFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P [Similar Products]
NCBI Protein Information
complement factor H-related protein 1
UniProt Protein Name
Complement factor H-related protein 1
UniProt Synonym Protein Names
H factor-like protein 1; H-factor-like 1; H36
UniProt Synonym Gene Names
CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2; FHR-1; H-factor-like 1 [Similar Products]
NCBI Summary for CFHR1
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]
UniProt Comments for CFHR1
Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
Research Articles on CFHR1
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Products associated with CFHR1 rtu elisa kit
Diseases associated with CFHR1 rtu elisa kit
Organs/Tissues associated with CFHR1 rtu elisa kit
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