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AGPAT1 recombinant protein :: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7007387 AGPAT1 recombinant protein
Unit / Price
0.01 mg  /  $885 +1 FREE 8GB USB
0.05 mg  /  $1,385 +1 FREE 8GB USB
0.1 mg  /  $2,310 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1), Recombinant Protein

 Also Known As   

Recombinant Human 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1)

 Product Gene Name   

AGPAT1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    G15 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    27-283aa; full length protein
 Sequence    FCSPSAKYFF KMAFYNGWIL FLAVLAIPVC AVRGRNVENM KILRLMLLHI KYLYGIRVEV RGAHHFPPSQ PYVVVSNHQS SLDLLGMMEV LPGRCVPIAK RELLWAGSAG LACWLAGVIF IDRKRTGDAI SVMSEVAQTL LTQDVRVWVF PEGTRNHNGS MLPFKRGAFH LAVQAQVPIV PIVMSSYQDF YCKKERRFTS GQCQVRVLPP VPTEGLTPDD VPALADRVRH SMLTVFREIS TDGRGGGDYL KKPGGGG
 OMIM    603099
 3D Structure    ModBase 3D Structure for Q99943
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 Host    E Coli
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 Form/Format    Liquid containing glycerol
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol.
 Tag Information    Tag type will be determined during the manufacturing process. Additional charge for tag removal. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of AGPAT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for AGPAT1 recombinant protein    Transmembrane Protein
 Application Notes for AGPAT1 recombinant protein    This is a recombinant transmembrane protein expressed in a cell-free expression system.
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NCBI/Uniprot data below describe general gene information for AGPAT1. It may not necessarily be applicable to this product.
 NCBI GI #    5453718
 NCBI GeneID    10554
 NCBI Accession #    NP_006402.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006411.3 [Other Products]
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 UniProt Primary Accession #    Q99943 [Other Products]
 UniProt Secondary Accession #    Q5BL03; A2BFI5 [Other Products]
 UniProt Related Accession #    Q99943 [Other Products]
 Molecular Weight    31,717 Da
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 NCBI Official Full Name    1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
 NCBI Official Synonym Full Names    1-acylglycerol-3-phosphate O-acyltransferase 1
 NCBI Official Symbol    AGPAT1 [Similar Products]
 NCBI Official Synonym Symbols   
G15; LPAATA; 1-AGPAT1; LPAAT-alpha
[Similar Products]
 NCBI Protein Information    1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
 UniProt Protein Name    1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
 UniProt Synonym Protein Names   
1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1; Lysophosphatidic acid acyltransferase alpha; LPAAT-alpha; Protein G15
 Protein Family    1-acyl-sn-glycerol-3-phosphate acyltransferase
 UniProt Gene Name    AGPAT1 [Similar Products]
 UniProt Synonym Gene Names    G15; 1-AGP acyltransferase 1; 1-AGPAT 1; LPAAT-alpha [Similar Products]
 UniProt Entry Name    PLCA_HUMAN
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 NCBI Summary for AGPAT1    This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AGPAT1    AGPAT1: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Protein type: Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Transferase; Membrane protein, integral; Membrane protein, multi-pass; Lipid Metabolism - ether lipid; EC 2.3.1.51

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane

Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; protein binding

Biological Process: CDP-diacylglycerol biosynthetic process; phosphatidic acid biosynthetic process; phospholipid metabolic process; positive regulation of cellular metabolic process; positive regulation of cytokine and chemokine mediated signaling pathway; positive regulation of cytokine production; triacylglycerol biosynthetic process
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 Research Articles on AGPAT1    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AGPAT1 recombinant proteinDiseases associated with AGPAT1 recombinant protein
 Products by Pathway  Pathway Diagram
 CDP-diacylglycerol Biosynthesis Pathway antibodies  CDP-diacylglycerol Biosynthesis Pathway Diagram
 CDP-diacylglycerol Biosynthesis I Pathway antibodies  CDP-diacylglycerol Biosynthesis I Pathway Diagram
 ChREBP Activates Metabolic Gene Expression Pathway antibodies  ChREBP Activates Metabolic Gene Expression Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >2 publications with AGPAT1 and Mental Disorders
 Fatty Liver Antibodies  >2 publications with AGPAT1 and Fatty Liver
 Liver Diseases Antibodies  >2 publications with AGPAT1 and Liver Diseases
 Inflammation Antibodies  >2 publications with AGPAT1 and Inflammation
 Ovarian Diseases Antibodies  >1 publications with AGPAT1 and Ovarian Diseases
 Disease Models, Animal Antibodies  >1 publications with AGPAT1 and Disease Models, Animal
 Weight Gain Antibodies  >1 publications with AGPAT1 and Weight Gain
 Glucose Intolerance Antibodies  >1 publications with AGPAT1 and Glucose Intolerance
 Cognition Disorders Antibodies  >1 publications with AGPAT1 and Cognition Disorders
 Necrosis Antibodies  >1 publications with AGPAT1 and Necrosis
Organs/Tissues associated with AGPAT1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >5 publications with AGPAT1 and Muscle
 Blood Antibodies  >5 publications with AGPAT1 and Blood
 Liver Antibodies  >4 publications with AGPAT1 and Liver
 Heart Antibodies  >3 publications with AGPAT1 and Heart
 Connective Tissue Antibodies  >3 publications with AGPAT1 and Connective Tissue
 Placenta Antibodies  >2 publications with AGPAT1 and Placenta
 Lung Antibodies  >2 publications with AGPAT1 and Lung
 Brain Antibodies  >2 publications with AGPAT1 and Brain
 Embryonic Tissue Antibodies  >1 publications with AGPAT1 and Embryonic Tissue
 Ovary Antibodies  >1 publications with AGPAT1 and Ovary
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