NP_056007.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
133,703 Da
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform a
NCBI Official Synonym Full Names
phospholipase C beta 1
NCBI Official Synonym Symbols
PLC-I; EIEE12; PI-PLC; PLC154; PLCB1A; PLCB1B; PLC-154; PLC-beta-1 [Similar Products]
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
UniProt Synonym Protein Names
PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1
UniProt Synonym Gene Names
NCBI Summary for PLCB1
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for PLCB1
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Research Articles on PLCB1
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Disclaimer
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Products associated with PLCB1 recombinant protein
Pathways associated with PLCB1 recombinant protein
Diseases associated with PLCB1 recombinant protein
Organs/Tissues associated with PLCB1 recombinant protein
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