NP_001124436.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
88,135 Da
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1
NCBI Official Synonym Full Names
phospholipase C delta 1
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
UniProt Synonym Protein Names
Phosphoinositide phospholipase C-delta-1; Phospholipase C-III; PLC-III; Phospholipase C-delta-1; PLC-delta-1
UniProt Synonym Gene Names
NCBI Summary for PLCD1
This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
UniProt Comments for PLCD1
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development.
Research Articles on PLCD1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with PLCD1 recombinant protein
Pathways associated with PLCD1 recombinant protein
Products by Pathway |
Pathway Diagram |
Calcium Signaling Pathway antibodies |
Calcium Signaling Pathway Diagram |
Calcium Signaling Pathway antibodies |
Calcium Signaling Pathway Diagram |
D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway antibodies |
D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway Diagram |
D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway antibodies |
D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway Diagram |
D-myo-inositol-5-phosphate Metabolism Pathway antibodies |
D-myo-inositol-5-phosphate Metabolism Pathway Diagram |
D-myo-inositol-5-phosphate Metabolism Pathway antibodies |
D-myo-inositol-5-phosphate Metabolism Pathway Diagram |
Inositol Phosphate Metabolism Pathway antibodies |
Inositol Phosphate Metabolism Pathway Diagram |
Inositol Phosphate Metabolism Pathway antibodies |
Inositol Phosphate Metabolism Pathway Diagram |
Inositol Phosphate Metabolism Pathway antibodies |
Inositol Phosphate Metabolism Pathway Diagram |
Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies |
Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram |
Diseases associated with PLCD1 recombinant protein
Organs/Tissues associated with PLCD1 recombinant protein
|