Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow PLCD3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • FAM59A Blocking Peptide
 • SOX17 Antibody
 • Thiamphenicol-Florenicol HRP Conjugate
 • SFTS Virus HB29 Blocking Peptide
 • ribosomal protein L38 (LOC100304552) Antibody
 • HAND1 Recombinant Protein
 • GPAA1 Antibody
 • Asialo GM2 Antibody
 • CHSY2 Antibody
 • D-2-hydroxyglutarate dehydrogenase, mitochondrial (D2hgdh) Recombinant Protein
 • CD32-CD16 Antibody
 • hyaluronan synthase 2 (HAS2) ELISA Kit
 • Total Epidermal Growth Factor (EGF) ELISA Kit
 • Golgi Glycoprotein 1 (GLG1) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

PLCD3 recombinant protein :: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (PLCD3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1423933 PLCD3 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,610 +2 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,610 +2 FREE 8GB USB
0.5 mg (Yeast)  /  $1,835 +2 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,835 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,765 +3 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,765 +3 FREE 8GB USB
1 mg (Yeast)  /  $3,225 +4 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $3,225 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (PLCD3), Recombinant Protein

 Also Known As   

Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (PLCD3)

 Product Synonym Names    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; EC=3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3
 Product Gene Name   

PLCD3 recombinant protein

[Similar Products]
 Product Synonym Gene Name    PLCD3; KIAA1964 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    1-789
 Sequence    MLCGRWRRCR RPPEEPPVAA QVAAQVAAPV ALPSPPTPSD GGTKRPGLRA LKKMGLTEDE DVRAMLRGSR LRKIRSRTWH KERLYRLQED GLSVWFQRRI PRAPSQHIFF VQHIEAVREG HQSEGLRRFG GAFAPARCLT IAFKGRRKNL DLAAPTAEEA QRWVRGLTKL RARLDAMSQR ERLDHWIHSY LHRADSNQDS KMSFKEIKSL LRMVNVDMND MYAYLLFKEC DHSNNDRLEG AEIEEFLRRL LKRPELEEIF HQYSGEDRVL SAPELLEFLE DQGEEGATLA RAQQLIQTYE LNETAKQHEL MTLDGFMMYL LSPEGAALDN THTCVFQDMN QPLAHYFISS SHNTYLTDSQ IGGPSSTEAY VRAFAQGCRC VELDCWEGPG GEPVIYHGHT LTSKILFRDV VQAVRDHAFT LSPYPVILSL ENHCGLEQQA AMARHLCTIL GDMLVTQALD SPNPEELPSP EQLKGRVLVK GKKLPAARSE DGRALSDREE EEEDDEEEEE EVEAAAQRRL AKQISPELSA LAVYCHATRL RTLHPAPNAP QPCQVSSLSE RKAKKLIREA GNSFVRHNAR QLTRVYPLGL RMNSANYSPQ EMWNSGCQLV ALNFQTPGYE MDLNAGRFLV NGQCGYVLKP ACLRQPDSTF DPEYPGPPRT TLSIQVLTAQ QLPKLNAEKP HSIVDPLVRI EIHGVPADCA RQETDYVLNN GFNPRWGQTL QFQLRAPELA LVRFVVEDYD ATSPNDFVGQ FTLPLSSLKQ GYRHIHLLSK DGASLSPATL FIQIRIQRS
 OMIM    608795
 3D Structure    ModBase 3D Structure for Q8N3E9
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Homo sapiens (Human)
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PLCD3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PLCD3. It may not necessarily be applicable to this product.
 NCBI GI #    19115964
 NCBI GeneID    113026
 NCBI Accession #    NP_588614.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_133373.4 [Other Products]
Section Bar
 UniProt Primary Accession #    Q8N3E9 [Other Products]
 UniProt Secondary Accession #    Q8TEC1; Q8TF37; Q96FL6 [Other Products]
 UniProt Related Accession #    Q8N3E9 [Other Products]
 Molecular Weight    89,258 Da
Table BarTOPTable Bar
 NCBI Official Full Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
 NCBI Official Synonym Full Names    phospholipase C, delta 3
 NCBI Official Symbol    PLCD3 [Similar Products]
 NCBI Official Synonym Symbols   
PLC-delta-3
[Similar Products]
 NCBI Protein Information    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; PLC delta3; phosphoinositide phospholipase C-delta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3
 UniProt Protein Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
 UniProt Synonym Protein Names   
Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3
 Protein Family    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
 UniProt Gene Name    PLCD3 [Similar Products]
 UniProt Synonym Gene Names    KIAA1964; PLC-delta-3 [Similar Products]
 UniProt Entry Name    PLCD3_HUMAN
Section Bar
 NCBI Summary for PLCD3    This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for PLCD3    PLCD3: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.

Protein type: Phospholipase; Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: plasma membrane; cytosol; cleavage furrow

Molecular Function: signal transducer activity; metal ion binding; phosphoinositide phospholipase C activity

Biological Process: inositol phosphate metabolic process; angiogenesis; lipid catabolic process; regulation of cell proliferation
Table BarTOPTable Bar
 Research Articles on PLCD3    1. PLCdelta3 regulates microvilli formation in enterocytes and the radial migration of neurons in the cerebral cortex of the developing brain. [review]
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with PLCD3 recombinant proteinPathways associated with PLCD3 recombinant protein
 Reference Product  PubMed Publications
 PLCD1 recombinant protein  >9 publications with PLCD3 and PLCD1
 PLCD4 recombinant protein  >2 publications with PLCD3 and PLCD4
 PIK3R2 recombinant protein  >1 publications with PLCD3 and PIK3R2
 DGKE recombinant protein  >1 publications with PLCD3 and DGKE
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol-5-phosphate Metabolism Pathway antibodies  D-myo-inositol-5-phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with PLCD3 recombinant proteinOrgans/Tissues associated with PLCD3 recombinant protein
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >4 publications with PLCD3 and Hypertension
 Brain Diseases Antibodies  >1 publications with PLCD3 and Brain Diseases
 Neoplasms Antibodies  >1 publications with PLCD3 and Neoplasms
 Nervous System Diseases Antibodies  >1 publications with PLCD3 and Nervous System Diseases
 Weight Loss Antibodies  >1 publications with PLCD3 and Weight Loss
 Breast Neoplasms Antibodies  >1 publications with PLCD3 and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with PLCD3 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with PLCD3 and Blood
 Heart Antibodies  >2 publications with PLCD3 and Heart
 Embryonic Tissue Antibodies  >2 publications with PLCD3 and Embryonic Tissue
 Liver Antibodies  >2 publications with PLCD3 and Liver
 Brain Antibodies  >2 publications with PLCD3 and Brain
 Connective Tissue Antibodies  >1 publications with PLCD3 and Connective Tissue
 Skin Antibodies  >1 publications with PLCD3 and Skin
 Muscle Antibodies  >1 publications with PLCD3 and Muscle
 Intestine Antibodies  >1 publications with PLCD3 and Intestine
 Testis Antibodies  >1 publications with PLCD3 and Testis
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions