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Plcd3 recombinant protein :: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (Plcd3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1373757 Plcd3 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $1,220 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,350 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,605 +2 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,650 +2 FREE 8GB USB
0.2 mg (Yeast)  /  $1,680 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,715 +2 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,820 +2 FREE 8GB USB
0.5 mg (Yeast)  /  $1,900 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,405 +3 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,445 +3 FREE 8GB USB
1 mg (E-Coli)  /  $2,570 +3 FREE 8GB USB
1 mg (Yeast)  /  $2,870 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $3,195 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (Plcd3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (Plcd3)

 Product Gene Name   

Plcd3 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Plcd3 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-785aa, full length protein
 Sequence    MLCGGWKRSR RSPEESRVSA QVAAPLAFPP SPASSDSSTK RPGLRALKKM GLTEDEDVQA MLRGSRLLKI RSRTWHKERL YRLQEDGLSV WFQRRIPRAA SKHIFFVQHI EAVREGHQSE GLRRFGGAFA PACCLTIAFK GRRKNLDLAA PTAEEAQRWV RGLAKLRARL DAMSQRERLD HWIHSYLHRA DSDQDSKMSF KEIKSLLRMV NVDMNDMYAY RLFKECDHSN NERLEGAEIE AFLRRLLKRP ELEEIFRRYS GEDRVLSASE LLEFLEDQGE DGATLACAQQ LIQTYELNET AKQHELMTLD GFMMYLLSPE GAALNVAHTC VFQDMGQPLA HYFISSSHNT YLTDSQIGGT SSTEAYIRAF AQGCRCVELD CWEGPGGEPV IYHGHTLTSK ILFRDVIQAV RDHAFTSSPY PVILSLENHC GLEQQAVMAR HLRSILGDML VTQALDSQNP EELPSPEQLK GRILVKGKKL PAARSEDGRI LSDREEEEEE EEEAEEALEA AEQRSRAKQI SPELSALAVY CCATRLRTLD PSPGPPQSCT VGSLSERKAR KFTREAGTSF VRHNTQQLTR VYPLGLRMNS ANYNPQEMWN SGCQLVALNF QTPGYEMDLN TGRFLINGQC GYVLKPAYLR QLNTTFDPEC PGPPRTTLAI QVLTAQQLPK LNAEKPSSIV DPLVRVEIHG VPEDCAQKET DYVLNNGFNP CWEQTLQFRL RAPELVLVRF VVEDYDTTSP NDFVGQSTLP LSSLKQGYRH IHLLSKDGAS LAPATLFVHI RIQNS
 3D Structure    ModBase 3D Structure for Q8K2J0
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Plcd3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Plcd3 recombinant protein

   This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
NCBI/Uniprot data below describe general gene information for Plcd3. It may not necessarily be applicable to this product.
 NCBI GI #    258645148
 NCBI GeneID    72469
 NCBI Accession #    NP_690026.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_152813.3 [Other Products]
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 UniProt Primary Accession #    Q8K2J0 [Other Products]
 UniProt Secondary Accession #    Q3UME8; Q69Z55; Q8BL19; A2AHR0; A2AHR1 [Other Products]
 UniProt Related Accession #    Q8K2J0 [Other Products]
 Molecular Weight    88,607 Da
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 NCBI Official Full Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
 NCBI Official Synonym Full Names    phospholipase C, delta 3
 NCBI Official Symbol    Plcd3 [Similar Products]
 NCBI Official Synonym Symbols   
mKIAA1964; 2610205J15Rik
[Similar Products]
 NCBI Protein Information    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
 UniProt Protein Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
 UniProt Synonym Protein Names   
Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3
 Protein Family    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
 UniProt Gene Name    Plcd3 [Similar Products]
 UniProt Synonym Gene Names    Kiaa1964; PLC-delta-3 [Similar Products]
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 UniProt Comments for Plcd3    Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.
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 Research Articles on Plcd3    1. Results indicate that PLCdelta1 and PLCdelta3 are required for cardiomyocyte survival and normal cardiac function.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Plcd3 recombinant proteinDiseases associated with Plcd3 recombinant protein
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol-5-phosphate Metabolism Pathway antibodies  D-myo-inositol-5-phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >5 publications with Plcd3 and Hypertension
 Nervous System Diseases Antibodies  >1 publications with Plcd3 and Nervous System Diseases
 Weight Loss Antibodies  >1 publications with Plcd3 and Weight Loss
 Breast Neoplasms Antibodies  >1 publications with Plcd3 and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with Plcd3 and Disease Models, Animal
Organs/Tissues associated with Plcd3 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with Plcd3 and Liver
 Heart Antibodies  >2 publications with Plcd3 and Heart
 Brain Antibodies  >2 publications with Plcd3 and Brain
 Embryonic Tissue Antibodies  >2 publications with Plcd3 and Embryonic Tissue
 Adipose Tissue Antibodies  >1 publications with Plcd3 and Adipose Tissue
 Connective Tissue Antibodies  >1 publications with Plcd3 and Connective Tissue
 Lung Antibodies  >1 publications with Plcd3 and Lung
 Inner Ear Antibodies  >1 publications with Plcd3 and Inner Ear
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