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Plcz1 recombinant protein :: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (Plcz1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1398219 Plcz1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $1,070 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,240 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,445 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,490 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,515 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,575 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,595 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,715 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,245 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,250 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,270 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,595 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $2,950 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (Plcz1), Recombinant Protein

 Also Known As   

Recombinant Rat 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (Plcz1)

 Product Gene Name   

Plcz1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Plcz1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-645aa, full length protein
 Sequence    MESHYELAEA RWFMSKIQDY FRGGKISAGI THKLLEKLDF PCHFAHVKRI FKENDRHNQG RITTEDFRTI YRCIVHREEI VEIFNTYTEN RKILPEDSLI EFLTQEQYEM EMDESSSVEI IQKYEPIAEV KNERQMSIEG FARYMFSSEC LLFKETCNTV YQDMNKPLND YYISSSHNTY LISDQILGPS DIWGYISALV KGCRCLEIDC WDGAQNEPIV YHGYTLTSKL LFKTVIQAIN KYAFVTSDYP VVLSLENHCS PGQQEVMTDI LQSTFGDFLL SDILDEFPDS LPSPEALKFK ILVKNKKVGT LSETRERLGT DKRGIALDLE EEIYENEDED SGKEPETWDD FLSRVKEEQE ADPSTLSGIA DAKKKIRKLR VALALSDLVI YTKAEKFRNF QYSRVYQQFN ETTSMGESRA RKLSKLRAHE FIFHTAAFIT RVYPKFTRAD SSNFNPQEFW NVGCQMVALN FQTPGLPMDL QNGKFLDNGG SGYVLKPDFL RDTTLGFNPN EPEGDGHPVT LTIRLISGIQ LPVNVPSNTS DIIVIIEVYG VPNDHMKQQS RAVKNNAFSP RWNETFTFLI QVPELALIRF VVETQGFLSG NELLGQYTLP VLCMNKGYRR VPLFSKSGAN LEPSSLFIYV WYYRE
 3D Structure    ModBase 3D Structure for Q5FX52
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Plcz1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Plcz1. It may not necessarily be applicable to this product.
 NCBI GI #    58866040
 NCBI GeneID    497197
 NCBI Accession #    NP_001012234.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001012234.1 [Other Products]
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 UniProt Primary Accession #    Q5FX52 [Other Products]
 UniProt Related Accession #    Q5FX52 [Other Products]
 Molecular Weight    74,315 Da
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 NCBI Official Full Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
 NCBI Official Synonym Full Names    phospholipase C, zeta 1
 NCBI Official Symbol    Plcz1 [Similar Products]
 NCBI Protein Information    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
 UniProt Protein Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
 UniProt Synonym Protein Names   
Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1
 Protein Family    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
 UniProt Gene Name    Plcz1 [Similar Products]
 UniProt Synonym Gene Names    PLC-zeta-1 [Similar Products]
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 UniProt Comments for Plcz1    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
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 Research Articles on Plcz1    1. All PLCZ1 proteins including fish could induce Ca(2+) oscillations in mouse eggs, but the activity was variable in the order of human >> mouse > medaka >> rat, estimated from minimal RNA concentration to induce Ca(2+) spikes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Plcz1 recombinant proteinPathways associated with Plcz1 recombinant protein
 Reference Product  PubMed Publications
 Itpr1 recombinant protein  >2 publications with Plcz1 and Itpr1
 Products by Pathway  Pathway Diagram
 CFTR Activity In The Plasma Membrane Pathway antibodies  CFTR Activity In The Plasma Membrane Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
 Oocyte Meiosis Pathway antibodies  Oocyte Meiosis Pathway Diagram
 Oocyte Meiosis Pathway antibodies  Oocyte Meiosis Pathway Diagram
 Phosphatidylinositol Signaling System Pathway antibodies  Phosphatidylinositol Signaling System Pathway Diagram
Diseases associated with Plcz1 recombinant proteinOrgans/Tissues associated with Plcz1 recombinant protein
 Disease Name  Pubmed Publications
 Pregnancy Complications Antibodies  >1 publications with Plcz1 and Pregnancy Complications
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >4 publications with Plcz1 and Testis
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