View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Sfn recombinant protein :: 14-3-3 protein sigma (Sfn) Recombinant Protein Catalog # MBS1102987 Unit / Price 0.02 mg (E-Coli) / $765 +1 FREE 8GB USB 0.1 mg (E-Coli) / $920 +1 FREE 8GB USB 0.02 mg (Yeast) / $925 +1 FREE 8GB USB 0.1 mg (Yeast) / $1,085 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,135 +1 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,405 +1 FREE 8GB USB 1 mg (E-Coli) / $1,625 +2 FREE 8GB USB 0.1 mg (Baculovirus) / $1,625 +2 FREE 8GB USB 1 mg (Yeast) / $2,120 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,210 +2 FREE 8GB USB 1 mg (Baculovirus) / $3,190 +3 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $5,900 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name 14-3-3 protein sigma (Sfn), Recombinant Protein Popular Item Full Product Name Recombinant Mouse 14-3-3 protein sigma (Sfn) Product Gene Name Sfn recombinant protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 1-248, Full length protein Sequence MERASLIQKA KLAEQAERYE DMAAFMKSAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VKEYREKVET ELRGVCDTVL GLLDSHLIKG AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADSAGEEGG EAPEEPQS 3D Structure ModBase 3D Structure for O70456 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Mouse Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of Sfn recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP SDS-PAGE of Sfn recombinant protein (Note: Representative image, actual molecular weight may vary depending on Tag type and expression host) TOP NCBI/Uniprot data below describe general gene information for Sfn. It may not necessarily be applicable to this product. NCBI GI # 134023662 NCBI GeneID 55948 NCBI Accession # NP_061224.2 [Other Products] NCBI GenBank Nucleotide # NM_018754.2 [Other Products] UniProt Primary Accession # O70456 [Other Products] UniProt Secondary Accession # Q3TEZ1[Other Products] UniProt Related Accession # O70456[Other Products] Molecular Weight 27,706 Da TOP NCBI Official Full Name 14-3-3 protein sigma NCBI Official Synonym Full Names stratifin NCBI Official Symbol Sfn [Similar Products] NCBI Official Synonym Symbols Er; Mme1; Ywhas [Similar Products] NCBI Protein Information 14-3-3 protein sigma UniProt Protein Name 14-3-3 protein sigma UniProt Synonym Protein Names Stratifin Protein Family 14-3-3 protein UniProt Gene Name Sfn [Similar Products] UniProt Synonym Gene Names Mkrn3 [Similar Products] TOP TOP UniProt Comments for Sfn Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. Research Articles on Sfn 1. Loss of 14-3-3-sigma sensitizes mice to chemically-induced skin carcinogenesis. Therefore, 14-3-3-sigma may indeed represent a mediator of tumor suppression in the skin. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with Sfn recombinant protein Reference Product PubMed Publications Trp53 recombinant protein >34 publications with Sfn and Trp53 Cdk1 recombinant protein >6 publications with Sfn and Cdk1 Trim25 recombinant protein >3 publications with Sfn and Trim25 Trp63 recombinant protein >2 publications with Sfn and Trp63 Krt17 recombinant protein >1 publications with Sfn and Krt17 Pathways associated with Sfn recombinant protein Products by Pathway Pathway Diagram Aldosterone-regulated Sodium Reabsorption Pathway antibodies Aldosterone-regulated Sodium Reabsorption Pathway Diagram Aldosterone-regulated Sodium Reabsorption Pathway antibodies Aldosterone-regulated Sodium Reabsorption Pathway Diagram Alpha6-Beta4 Integrin Signaling Pathway antibodies Alpha6-Beta4 Integrin Signaling Pathway Diagram Calcium Regulation In The Cardiac Cell Pathway antibodies Calcium Regulation In The Cardiac Cell Pathway Diagram Cell Cycle Pathway antibodies Cell Cycle Pathway Diagram Cell Cycle Pathway antibodies Cell Cycle Pathway Diagram Cell Cycle Signaling Pathway antibodies Cell Cycle Signaling Pathway Diagram Myometrial Relaxation And Contraction Pathways antibodies Myometrial Relaxation And Contraction Pathways Diagram P53 Signaling Pathway antibodies P53 Signaling Pathway Diagram P53 Signaling Pathway antibodies P53 Signaling Pathway Diagram Diseases associated with Sfn recombinant protein Disease Name Pubmed Publications Neoplasms Antibodies >273 publications with Sfn and Neoplasms Carcinoma Antibodies >144 publications with Sfn and Carcinoma Adenocarcinoma Antibodies >60 publications with Sfn and Adenocarcinoma Nervous System Diseases Antibodies >60 publications with Sfn and Nervous System Diseases Breast Neoplasms Antibodies >60 publications with Sfn and Breast Neoplasms Gastrointestinal Diseases Antibodies >43 publications with Sfn and Gastrointestinal Diseases Necrosis Antibodies >41 publications with Sfn and Necrosis Peripheral Nervous System Diseases Antibodies >35 publications with Sfn and Peripheral Nervous System Diseases Prostatic Neoplasms Antibodies >34 publications with Sfn and Prostatic Neoplasms Drug Toxicity Antibodies >32 publications with Sfn and Drug Toxicity Organs/Tissues associated with Sfn recombinant protein Organ/Tissue Name Pubmed Publications Skin Antibodies >84 publications with Sfn and Skin Lung Antibodies >40 publications with Sfn and Lung Liver Antibodies >33 publications with Sfn and Liver Brain Antibodies >23 publications with Sfn and Brain Intestine Antibodies >16 publications with Sfn and Intestine Heart Antibodies >10 publications with Sfn and Heart Kidney Antibodies >9 publications with Sfn and Kidney Eye Antibodies >8 publications with Sfn and Eye Pancreas Antibodies >7 publications with Sfn and Pancreas Stomach Antibodies >6 publications with Sfn and Stomach TOP © 2006-24 MyBioSource.com. All rights reserved. Privacy Policy | Terms & Conditions Our Best Sellers Hepatocyte Growth Factor Receptor (HGFR) ELISA Kit His-tag Antibody FBLN2 Antibody NLRC5 Antibody CD82 molecule Antibody TAPBP Antibody Hemagglutinin-esterase (HE) Recombinant Protein IGFBP3 Antibody ELISA Antibodies Secondary Antibodies Antigens Biochemicals cDNA Clones Kits Peptides Rec Proteins Protein Family Request a Quote Please fill out the form below and our representative will get back to you shortly. Catalog # MBS000000 Your E-mail (required) Ship to Country (required) United StatesAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegowinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCook IslandsCosta RicaCote DIvoireCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrance MetropolitanFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuineaGuinea-bissauGuyanaHaitiHeard and Mc Donald IslandsHondurasHong KongHungaryIcelandIndiaIndonesiaIran (Islamic Republic of)IraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiKorea Democratic People Republic ofKorea Republic ofKuwaitKyrgyzstanLao People Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacauMacedonia The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesia Federated States ofMoldova Republic ofMonacoMongoliaMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorthern Mariana IslandsNorwayOmanPakistanPalauPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarReunionRomaniaRussian FederationRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSeychellesSierra LeoneSingaporeSlovakia (Slovak Republic)SloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSpainSri LankaSt. HelenaSt. Pierre and MiquelonSudanSurinameSvalbard and Jan Mayen IslandsSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania United Republic ofThailandTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUnited States Minor Outlying IslandsUruguayUzbekistanVanuatuVatican City State (Holy See)VenezuelaViet NamVirgin Islands (British)Virgin Islands (U.S.)Wallis and Futuna IslandsWestern SaharaYemenYugoslaviaZaireZambiaZimbabwe Postal/Zip Code (required) Your Name Your Telephone Your Inquiries, Comments or Full Shipping Address (required) Contact Us Please fill out the form below and our representative will get back to you shortly. Inquiry for # MBS000000 Your Name Your Telephone Your E-mail (required) Your Inquiries or Comments