NP_000851.2
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,526 Da
NCBI Official Full Name
15-hydroxyprostaglandin dehydrogenase
NCBI Official Synonym Full Names
15-hydroxyprostaglandin dehydrogenase
NCBI Official Synonym Symbols
PGDH; PGDH1; PHOAR1; 15-PGDH; SDR36C1 [Similar Products]
NCBI Protein Information
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
UniProt Protein Name
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
UniProt Synonym Protein Names
Prostaglandin dehydrogenase 1; Short chain dehydrogenase/reductase family 36C member 1
UniProt Synonym Gene Names
NCBI Summary for HPGD
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
UniProt Comments for HPGD
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
Research Articles on HPGD
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with HPGD recombinant protein
Pathways associated with HPGD recombinant protein
Diseases associated with HPGD recombinant protein
Disease Name |
Pubmed Publications |
Osteoarthropathy, Primary Hypertrophic Antibodies |
>16 publications with HPGD and Osteoarthropathy, Primary Hypertrophic |
HYPERTROPHIC OSTEOARTHROPATHY, PRIMARY, AUTOSOMAL RECESSIVE, 1 Antibodies |
>16 publications with HPGD and HYPERTROPHIC OSTEOARTHROPATHY, PRIMARY, AUTOSOMAL RECESSIVE, 1 |
Inflammation Antibodies |
>11 publications with HPGD and Inflammation |
Breast Neoplasms Antibodies |
>3 publications with HPGD and Breast Neoplasms |
Fibrosis Antibodies |
>2 publications with HPGD and Fibrosis |
Fetal Growth Retardation Antibodies |
>2 publications with HPGD and Fetal Growth Retardation |
Pain Antibodies |
>2 publications with HPGD and Pain |
Disease Models, Animal Antibodies |
>2 publications with HPGD and Disease Models, Animal |
Prostatic Neoplasms Antibodies |
>2 publications with HPGD and Prostatic Neoplasms |
Neoplasms, Experimental Antibodies |
>1 publications with HPGD and Neoplasms, Experimental |
Organs/Tissues associated with HPGD recombinant protein
|