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Hpgd recombinant protein :: 15-hydroxyprostaglandin dehydrogenase [NAD (+)] (Hpgd) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1237622 Hpgd recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $670 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $900 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $950 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $990 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,080 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,190 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,195 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,225 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,395 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,725 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,810 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,860 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,300 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

15-hydroxyprostaglandin dehydrogenase [NAD (+)] (Hpgd), Recombinant Protein

 Also Known As   

Recombinant Rat 15-hydroxyprostaglandin dehydrogenase [NAD (+)] (Hpgd)

 Product Gene Name   

Hpgd recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-266aa, Full length protein
 Sequence    MHVNGKVALV TGAAQGIGKA FTEALLLHGA KVALVDWNLE TGVKCKAALD EQFEPQKTLF IQCDVADQKQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EQTLQINLVS VISGTYLGLD YMSKQNGGEG GIIINISSIA GLMPVAQQPV YCASKHGIIG FTRSAAMAAN LMKSGVRLNV ICPGFVKTPI LESIEKEENM GQYIEYTDQI KAMMKFYGIL DPSAIANGLI NLIEDDALNG AIMKITASKG IHFQDYDLFP SFSKAP
 3D Structure    ModBase 3D Structure for O08699
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Hpgd recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Hpgd recombinant protein

   This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for Hpgd. It may not necessarily be applicable to this product.
 NCBI GI #    40538858
 NCBI GeneID    79242
 NCBI Accession #    NP_077366.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_024390.2 [Other Products]
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 UniProt Primary Accession #    O08699 [Other Products]
 UniProt Secondary Accession #    Q6P687 [Other Products]
 UniProt Related Accession #    O08699 [Other Products]
 Molecular Weight    28,939 Da
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 NCBI Official Full Name    15-hydroxyprostaglandin dehydrogenase
 NCBI Official Synonym Full Names    15-hydroxyprostaglandin dehydrogenase
 NCBI Official Symbol    Hpgd [Similar Products]
 NCBI Protein Information    15-hydroxyprostaglandin dehydrogenase [NAD(+)]
 UniProt Protein Name    15-hydroxyprostaglandin dehydrogenase [NAD(+)]
 UniProt Synonym Protein Names   
Prostaglandin dehydrogenase 1
 Protein Family    15-hydroxyprostaglandin dehydrogenase
 UniProt Gene Name    Hpgd [Similar Products]
 UniProt Synonym Gene Names    Pgdh1; 15-PGDH [Similar Products]
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 NCBI Summary for Hpgd    NAD+-dependent 15-hydroxyprostaglandin dehydrogenase [RGD, Feb 2006]
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 UniProt Comments for Hpgd    Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 ().
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 Research Articles on Hpgd    1. Results showed that 15-PGDH mRNA and protein expression was reduced in the hypothalamus and lungs in stressed animals compared with controls, which was correlated with a reduction of enzymatic activity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Hpgd recombinant proteinDiseases associated with Hpgd recombinant protein
 Products by Pathway  Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13 publications with Hpgd and Neoplasms
 Osteoarthropathy, Primary Hypertrophic Antibodies  >8 publications with Hpgd and Osteoarthropathy, Primary Hypertrophic
 Inflammation Antibodies  >5 publications with Hpgd and Inflammation
 Colorectal Neoplasms Antibodies  >4 publications with Hpgd and Colorectal Neoplasms
 Skin Diseases Antibodies  >3 publications with Hpgd and Skin Diseases
 Carcinoma, Squamous Cell Antibodies  >2 publications with Hpgd and Carcinoma, Squamous Cell
 Fibrosis Antibodies  >2 publications with Hpgd and Fibrosis
 Adenocarcinoma Antibodies  >2 publications with Hpgd and Adenocarcinoma
 HYPERTROPHIC OSTEOARTHROPATHY, PRIMARY, AUTOSOMAL RECESSIVE, 1 Antibodies  >2 publications with Hpgd and HYPERTROPHIC OSTEOARTHROPATHY, PRIMARY, AUTOSOMAL RECESSIVE, 1
 Prostatic Neoplasms Antibodies  >2 publications with Hpgd and Prostatic Neoplasms
Organs/Tissues associated with Hpgd recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >3 publications with Hpgd and Prostate
 Lung Antibodies  >2 publications with Hpgd and Lung
 Small Intestine Antibodies  >2 publications with Hpgd and Small Intestine
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