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SEP15 recombinant protein :: 15 kDa selenoprotein (SEP15) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1019633 SEP15 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $530 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $690 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $705 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $775 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $845 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $935 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,050 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,065 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,085 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,095 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,545 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,595 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,655 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,070 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

15 kDa selenoprotein (SEP15), Recombinant Protein

 Also Known As   

Recombinant Human 15 kDa selenoprotein (SEP15)

 Product Synonym Names    15 kDa selenoprotein
 Product Gene Name   

SEP15 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    29-162aa; full length protein
 Sequence    FG AEFSSEACRE LGFSSNLLCS SCDLLGQFNL LQLDPDCRGC CQEEAQFETK KLYAGAILEV CGUKLGRFPQ VQAFVRSDKP KLFRGLQIKY VRGSDPVLKL LDDNGNIAEE LSILKWNTDS VEEFLSEKLE RI
 OMIM    606254
 3D Structure    ModBase 3D Structure for O60613
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SEP15 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for SEP15. It may not necessarily be applicable to this product.
 NCBI GI #    42741648
 NCBI GeneID    9403
 NCBI Accession #    NP_004252.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004261.3 [Other Products]
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 UniProt Primary Accession #    O60613 [Other Products]
 UniProt Secondary Accession #    Q4GZG7; Q8WU00; Q9BS64; Q9GZW0; Q9NR01 [Other Products]
 UniProt Related Accession #    O60613 [Other Products]
 Molecular Weight    13,219 Da
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 NCBI Official Full Name    15 kDa selenoprotein isoform 1
 NCBI Official Symbol    SEP15 [Similar Products]
 NCBI Protein Information    15 kDa selenoprotein
 UniProt Protein Name    15 kDa selenoprotein
 UniProt Gene Name    SEP15 [Similar Products]
 UniProt Entry Name    SEP15_HUMAN
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 NCBI Summary for SEP15    This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SEP15    SEP15: May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum. Belongs to the selenoprotein M/SEP15 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1p31

Cellular Component: endoplasmic reticulum lumen

Molecular Function: selenium binding

Biological Process: 'de novo' posttranslational protein folding
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 Research Articles on SEP15    1. This study provides evidence that SEP15 genetic variation may influence prostate cancer mortality
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with SEP15 recombinant proteinDiseases associated with SEP15 recombinant protein
 Products by Pathway  Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms, Experimental Antibodies  >2 publications with SEP15 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >2 publications with SEP15 and Breast Neoplasms
 Inflammation Antibodies  >2 publications with SEP15 and Inflammation
 Urinary Bladder Neoplasms Antibodies  >2 publications with SEP15 and Urinary Bladder Neoplasms
 Body Weight Changes Antibodies  >1 publications with SEP15 and Body Weight Changes
 Death Antibodies  >1 publications with SEP15 and Death
 Cell Transformation, Neoplastic Antibodies  >1 publications with SEP15 and Cell Transformation, Neoplastic
Organs/Tissues associated with SEP15 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13 publications with SEP15 and Blood
 Prostate Antibodies  >11 publications with SEP15 and Prostate
 Liver Antibodies  >9 publications with SEP15 and Liver
 Brain Antibodies  >7 publications with SEP15 and Brain
 Kidney Antibodies  >5 publications with SEP15 and Kidney
 Muscle Antibodies  >5 publications with SEP15 and Muscle
 Lung Antibodies  >4 publications with SEP15 and Lung
 Thyroid Antibodies  >4 publications with SEP15 and Thyroid
 Testis Antibodies  >4 publications with SEP15 and Testis
 Skin Antibodies  >2 publications with SEP15 and Skin
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