NP_035804.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,249 Da
NCBI Official Full Name
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
NCBI Official Synonym Full Names
UDP galactosyltransferase 8A
NCBI Official Synonym Symbols
Cgt; Ugt8; mCerGT; AI850488; AW455908 [Similar Products]
NCBI Protein Information
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
UniProt Protein Name
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
UniProt Synonym Protein Names
Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose-ceramide galactosyltransferase
UniProt Synonym Gene Names
UniProt Entry Name
CGT_MOUSE
UniProt Comments for Ugt8
UGT8: Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Belongs to the UDP-glycosyltransferase family.
Protein type: Membrane protein, integral; EC 2.4.1.45; Transferase; Lipid Metabolism - sphingolipid
Cellular Component: integral to membrane; intracellular membrane-bound organelle; membrane
Molecular Function: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity; ceramide glucosyltransferase activity; glucuronosyltransferase activity; transferase activity; transferase activity, transferring glycosyl groups; transferase activity, transferring hexosyl groups; UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity
Biological Process: cytoskeleton organization and biogenesis; flavonoid biosynthetic process; glycolipid biosynthetic process; lipid metabolic process; metabolic process; myelination; neurite morphogenesis; paranodal junction assembly; sphingolipid metabolic process
Research Articles on Ugt8
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Pathways associated with Ugt8 recombinant protein
Diseases associated with Ugt8 recombinant protein
Organs/Tissues associated with Ugt8 recombinant protein
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