NP_001239211.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53.84 kDa
NCBI Official Full Name
2-oxoglutarate dehydrogenase, mitochondrial isoform 1
NCBI Official Synonym Full Names
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
NCBI Official Synonym Symbols
d1401; AA409584; mKIAA4192; 2210403E04Rik; 2210412K19Rik [Similar Products]
NCBI Protein Information
2-oxoglutarate dehydrogenase, mitochondrial
UniProt Protein Name
2-oxoglutarate dehydrogenase, mitochondrial
UniProt Synonym Protein Names
2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase
UniProt Synonym Gene Names
UniProt Comments for Ogdh
OGDH: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - citrate (TCA) cycle; EC 1.2.4.2; Mitochondrial; Oxidoreductase
Chromosomal Location of Human Ortholog: 11|11 A1
Cellular Component: mitochondrion; oxoglutarate dehydrogenase complex
Molecular Function: chaperone binding; heat shock protein binding; oxoglutarate dehydrogenase (succinyl-transferring) activity
Biological Process: 2-oxoglutarate metabolic process; cerebellar cortex development; hippocampus development; NADH metabolic process; pyramidal neuron development; striatum development; succinyl-CoA metabolic process; tangential migration from the subventricular zone to the olfactory bulb; thalamus development; tricarboxylic acid cycle
Research Articles on Ogdh
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Pathways associated with Ogdh recombinant protein
Diseases associated with Ogdh recombinant protein
Organs/Tissues associated with Ogdh recombinant protein
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