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Ogdh recombinant protein :: 2-oxoglutarate dehydrogenase Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1438331
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $195 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $255 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $420 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $665 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $850 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $995 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,090 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,145 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,230 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,250 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,290 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,800 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,870 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,965 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,395 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

2-oxoglutarate dehydrogenase (Ogdh), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse 2-oxoglutarate dehydrogenase, mitochondrial 

 Product Synonym Names    2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase
 Product Gene Name   

Ogdh recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1438331 COA    COA PDF
 Sequence Positions    695-1023. Partial.
 Sequence    VDKRTCIPMN HLWPNQAPYT VCNSSLSEYG VLGFELGFAM ASPNALVLWE AQFGDFNNMA QCIIDQFICP GQAKWVRQNG IVLLLPHGME GMGPEHSSAR PERFLQMCND DPDVLPDLQE ENFDINQLYD CNWIVVNCST PGNFFHVLRR QILLPFRKPL IVFTPKSLLR HPEARTSFDE MLPGTHFQRV IPENGPAAQD PHKVKRLLFC TGKVYYDLTR ERKARNMEEE VAITRIEQLS PFPFDLLLKE AQKYPNAELA WCQEEHKNQG YYDYVKPRLR TTIDRAKPVW YAGRDPAAAP ATGNKKTHLT ELQRFLDTAF DLDAFKKFS
 3D Structure    ModBase 3D Structure for Q60597
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ogdh recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Ogdh recombinant protein

   The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
 Product Categories/Family for Ogdh recombinant protein    Metabolism
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 SDS-PAGE of Ogdh recombinant protein    Ogdh recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Ogdh. It may not necessarily be applicable to this product.
 NCBI GI #    356582477
 NCBI GeneID    18293
 NCBI Accession #    NP_001239211.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001252282.1 [Other Products]
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 UniProt Primary Accession #    Q60597 [Other Products]
 UniProt Secondary Accession #    Q3UDM7; Q5DTI4; Q5SVX7; Q5SVX9; Q6PFZ2; Q80Y57; Q8K0K7; Q8K2Z3; Q8R3M2; Q91WP2 [Other Products]
 UniProt Related Accession #    Q60597 [Other Products]
 Molecular Weight    53.84kD
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 NCBI Official Full Name    2-oxoglutarate dehydrogenase, mitochondrial isoform 1
 NCBI Official Synonym Full Names    oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
 NCBI Official Symbol    Ogdh [Similar Products]
 NCBI Official Synonym Symbols   
d1401; AA409584; mKIAA4192; 2210403E04Rik; 2210412K19Rik
[Similar Products]
 NCBI Protein Information    2-oxoglutarate dehydrogenase, mitochondrial
 UniProt Protein Name    2-oxoglutarate dehydrogenase, mitochondrial
 UniProt Synonym Protein Names   
2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase
 Protein Family    2-oxoglutarate dehydrogenase
 UniProt Gene Name    Ogdh [Similar Products]
 UniProt Synonym Gene Names    Kiaa4192; OGDC-E1 [Similar Products]
 UniProt Entry Name    ODO1_MOUSE
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 UniProt Comments for Ogdh    OGDH: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - citrate (TCA) cycle; Mitochondrial; Oxidoreductase; EC 1.2.4.2

Cellular Component: mitochondrion; oxoglutarate dehydrogenase complex

Molecular Function: chaperone binding; heat shock protein binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamin pyrophosphate binding

Biological Process: 2-oxoglutarate metabolic process; glycolysis; metabolic process; NADH metabolic process; succinyl-CoA metabolic process; tricarboxylic acid cycle
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Product References and Citations for Ogdh recombinant protein

   "Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R.F., Ohara R., Inamoto S., Nagase T., Ohara O., Koga H. Submitted (FEB-2005)
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 Research Articles on Ogdh    1. The nitration degree of alpha-OGDH for diabetic mouse is higher than that for control mouse, indicating that alpha-OGDH of the diabetic mouse suffered from more intense oxidative damage.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Ogdh recombinant proteinPathways associated with Ogdh recombinant protein
 Reference Product  PubMed Publications
 Idh3a recombinant protein  >1 publications with Ogdh and Idh3a
 Idh2 recombinant protein  >1 publications with Ogdh and Idh2
 Dlst recombinant protein  >1 publications with Ogdh and Dlst
 Products by Pathway  Pathway Diagram
 2-amino-3-carboxymuconate Semialdehyde Degradation To Glutaryl-CoA Pathway antibodies  2-amino-3-carboxymuconate Semialdehyde Degradation To Glutaryl-CoA Pathway Diagram
 2-ketoglutarate Dehydrogenase Complex Pathway antibodies  2-ketoglutarate Dehydrogenase Complex Pathway Diagram
 Amino Acid Metabolism Pathway antibodies  Amino Acid Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
Diseases associated with Ogdh recombinant proteinOrgans/Tissues associated with Ogdh recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4 publications with Ogdh and Nervous System Diseases
 Heart Diseases Antibodies  >3 publications with Ogdh and Heart Diseases
 Cardiovascular Diseases Antibodies  >3 publications with Ogdh and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >2 publications with Ogdh and Breast Neoplasms
 Brain Diseases Antibodies  >2 publications with Ogdh and Brain Diseases
 Disease Models, Animal Antibodies  >2 publications with Ogdh and Disease Models, Animal
 Liver Diseases Antibodies  >2 publications with Ogdh and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with Ogdh and Cell Transformation, Neoplastic
 Liver Cirrhosis Antibodies  >1 publications with Ogdh and Liver Cirrhosis
 Fatty Liver Antibodies  >1 publications with Ogdh and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >16 publications with Ogdh and Muscle
 Heart Antibodies  >9 publications with Ogdh and Heart
 Liver Antibodies  >8 publications with Ogdh and Liver
 Brain Antibodies  >6 publications with Ogdh and Brain
 Pancreas Antibodies  >3 publications with Ogdh and Pancreas
 Kidney Antibodies  >3 publications with Ogdh and Kidney
 Stomach Antibodies  >2 publications with Ogdh and Stomach
 Connective Tissue Antibodies  >2 publications with Ogdh and Connective Tissue
 Bone Antibodies  >2 publications with Ogdh and Bone
 Eye Antibodies  >1 publications with Ogdh and Eye
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