NP_001265667.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,116 Da
NCBI Official Full Name
24-hydroxycholesterol 7-alpha-hydroxylase isoform 2
NCBI Official Synonym Full Names
cytochrome P450 family 39 subfamily A member 1
NCBI Protein Information
24-hydroxycholesterol 7-alpha-hydroxylase
UniProt Protein Name
24-hydroxycholesterol 7-alpha-hydroxylase
UniProt Synonym Protein Names
Cytochrome P450 39A1; hCYP39A1; Oxysterol 7-alpha-hydroxylase
UniProt Synonym Gene Names
NCBI Summary for CYP39A1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
UniProt Comments for CYP39A1
Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha-hydroxylated product.
Research Articles on CYP39A1
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Products associated with CYP39A1 recombinant protein
Pathways associated with CYP39A1 recombinant protein
Diseases associated with CYP39A1 recombinant protein
Organs/Tissues associated with CYP39A1 recombinant protein
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