NP_062011.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
48,227 Da
NCBI Official Full Name
25-hydroxycholesterol 7-alpha-hydroxylase
NCBI Official Synonym Full Names
cytochrome P450 family 7 subfamily B member 1
NCBI Protein Information
25-hydroxycholesterol 7-alpha-hydroxylase
UniProt Protein Name
25-hydroxycholesterol 7-alpha-hydroxylase
UniProt Synonym Protein Names
Cytochrome P450 7B1; Hippocampal transcript 1 protein; HCT-1; Oxysterol 7-alpha-hydroxylase
UniProt Synonym Gene Names
NCBI Summary for Cyp7b1
member of the p450 subfamily of cholesterol metabolizing enzymes that performs 7alpha-hydroxylation of 27-hydroxycholesterol in a bile synthesis pathway alternative to the classical cholesterol disposal pathway [RGD, Feb 2006]
UniProt Comments for Cyp7b1
Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) from 25-hydroxycholesterol. Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
Research Articles on Cyp7b1
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Products associated with Cyp7b1 recombinant protein
Pathways associated with Cyp7b1 recombinant protein
Diseases associated with Cyp7b1 recombinant protein
Organs/Tissues associated with Cyp7b1 recombinant protein
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