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Psmc3 recombinant protein :: 26S protease regulatory subunit 6A (Psmc3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1097363 Psmc3 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $860 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,080 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,150 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,270 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,285 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,330 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,370 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,450 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,805 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,970 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,010 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,210 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,595 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

26S protease regulatory subunit 6A (Psmc3), Recombinant Protein

 Also Known As   

Recombinant Mouse 26S protease regulatory subunit 6A (Psmc3)

 Product Gene Name   

Psmc3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-442aa, Full length protein
 Sequence    MQEMNLLPTP ESPVTRQEKM ATVWDEAEQD GIGEEVLKMS TEEIVQRTRL LDSEIKIMKS EVLRVTHELQ AMKDKIKENS EKIKVNKTLP YLVSNVIELL DVDPNDQEED GANIDLDSQR KGKCAVIKTS TRQTYFLPVI GLVDAEKLKP GDLVGVNKDS YLILETLPTE YDSRVKAMEV DERPTEQYSD IGGLDKQIQE LVEAIVLPMN HKEKFENLGI QPPKGVLMYG PPGTGKTLLA RACAAQTKAT FLKLAGPQLV QMFIGDGAKL VRDAFALAKE KAPSIIFIDE LDAIGTKRFD SEKAGDREVQ RTMLELLNQL DGFQPNTQVK VIAATNRVDI LDPALLRSGR LDRKIEFPMP NEEARARIMQ IHSRKMNVSP DVNYEELARC TDDFNGAQCK AVCVEAGMIA LRRGATELTH EDYMEGILEV QAKKKANLQY YA
 3D Structure    ModBase 3D Structure for O88685
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Psmc3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Psmc3 recombinant protein

   The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP
ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.
NCBI/Uniprot data below describe general gene information for Psmc3. It may not necessarily be applicable to this product.
 NCBI GI #    228008337
 NCBI GeneID    19182
 NCBI Accession #    NP_032974.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_008948.2 [Other Products]
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 UniProt Primary Accession #    O88685 [Other Products]
 UniProt Secondary Accession #    Q99JN8 [Other Products]
 UniProt Related Accession #    O88685 [Other Products]
 Molecular Weight    49,549 Da
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 NCBI Official Full Name    26S proteasome regulatory subunit 6A
 NCBI Official Synonym Full Names    proteasome (prosome, macropain) 26S subunit, ATPase 3
 NCBI Official Symbol    Psmc3 [Similar Products]
 NCBI Official Synonym Symbols   
TBP-1
[Similar Products]
 NCBI Protein Information    26S proteasome regulatory subunit 6A
 UniProt Protein Name    26S proteasome regulatory subunit 6A
 UniProt Synonym Protein Names   
26S proteasome AAA-ATPase subunit RPT5; Proteasome 26S subunit ATPase 3; Tat-binding protein 1; TBP-1
 Protein Family    26S protease regulatory
 UniProt Gene Name    Psmc3 [Similar Products]
 UniProt Synonym Gene Names    Tbp1; TBP-1 [Similar Products]
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 UniProt Comments for Psmc3    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Psmc3 recombinant proteinPathways associated with Psmc3 recombinant protein
 Reference Product  PubMed Publications
 Psmc2 recombinant protein  >3 publications with Psmc3 and Psmc2
 Psmc5 recombinant protein  >2 publications with Psmc3 and Psmc5
 Psmc1 recombinant protein  >1 publications with Psmc3 and Psmc1
 Psmd4 recombinant protein  >1 publications with Psmc3 and Psmd4
 Products by Pathway  Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies  APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 AUF1 (hnRNP D0) Destabilizes MRNA Pathway antibodies  AUF1 (hnRNP D0) Destabilizes MRNA Pathway Diagram
 Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 Activation Of NF-kappaB In B Cells Pathway antibodies  Activation Of NF-kappaB In B Cells Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
Diseases associated with Psmc3 recombinant proteinOrgans/Tissues associated with Psmc3 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4 publications with Psmc3 and Nervous System Diseases
 Brain Diseases Antibodies  >4 publications with Psmc3 and Brain Diseases
 Immune System Diseases Antibodies  >3 publications with Psmc3 and Immune System Diseases
 Necrosis Antibodies  >3 publications with Psmc3 and Necrosis
 HIV Infections Antibodies  >3 publications with Psmc3 and HIV Infections
 Cell Transformation, Neoplastic Antibodies  >1 publications with Psmc3 and Cell Transformation, Neoplastic
 Prostatic Diseases Antibodies  >1 publications with Psmc3 and Prostatic Diseases
 Infertility, Male Antibodies  >1 publications with Psmc3 and Infertility, Male
 Carcinoma, Hepatocellular Antibodies  >1 publications with Psmc3 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >1 publications with Psmc3 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with Psmc3 and Brain
 Testis Antibodies  >7 publications with Psmc3 and Testis
 Blood Antibodies  >5 publications with Psmc3 and Blood
 Muscle Antibodies  >2 publications with Psmc3 and Muscle
 Uterus Antibodies  >1 publications with Psmc3 and Uterus
 Bladder Antibodies  >1 publications with Psmc3 and Bladder
 Ovary Antibodies  >1 publications with Psmc3 and Ovary
 Stomach Antibodies  >1 publications with Psmc3 and Stomach
 Prostate Antibodies  >1 publications with Psmc3 and Prostate
 Lung Antibodies  >1 publications with Psmc3 and Lung
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