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Psmc5 recombinant protein :: 26S protease regulatory subunit 8 (Psmc5) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS949981 Psmc5 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $820 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,050 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,095 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,210 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,240 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,300 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,335 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,405 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,715 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,920 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,970 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,135 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,530 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

26S protease regulatory subunit 8 (Psmc5), Recombinant Protein

 Also Known As   

Recombinant Rat 26S protease regulatory subunit 8 (Psmc5)

 Product Gene Name   

Psmc5 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-406aa, Full Length of Mature Protein
 Sequence    ALDGPEQMEL EEGKAGSGLR QYYLSKIEEL QLIVNDKSQN LRRLQAQRNE LNAKVRLLRE ELQLLQEQGS YVGEVVRAMD KKKVLVKVHP EGKFVVDVDK NIDINDVTPN CRVALRNDSY TLHKILPNKV DPLVSLMMVE KVPDSTYEMI GGLDKQIKEI KEVIELPVKH PELFEALGIA QPKGVLLYGP PGTGKTLLAR AVAHHTDCTF IRVSGSELVQ KFIGEGARMV RELFVMAREH APSIIFMDEI DSIGSSRLEG GSGGDSEVQR TMLELLNQLD GFEATKNIKV IMATNRIDIL DSALLRPGRI DRKIEFPPPN EEARLDILKI HSRKMNLTRG INLRKIAELM PGASGAEVKG VCTEAGMYAL RERRVHVTQE DFEMAVAKVM QKDSEKNMSI KKLWK
 3D Structure    ModBase 3D Structure for P62198
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Psmc5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Psmc5 recombinant protein

   The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP
ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.
NCBI/Uniprot data below describe general gene information for Psmc5. It may not necessarily be applicable to this product.
 NCBI GI #    13592141
 NCBI GeneID    81827
 NCBI Accession #    NP_112411.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_031149.1 [Other Products]
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 UniProt Primary Accession #    P62198 [Other Products]
 UniProt Secondary Accession #    O35051; P47210; P52915; P52916 [Other Products]
 UniProt Related Accession #    P62198 [Other Products]
 Molecular Weight    45,626 Da
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 NCBI Official Full Name    26S proteasome regulatory subunit 8
 NCBI Official Synonym Full Names    proteasome 26S subunit, ATPase 5
 NCBI Official Symbol    Psmc5 [Similar Products]
 NCBI Official Synonym Symbols   
Sug1
[Similar Products]
 NCBI Protein Information    26S proteasome regulatory subunit 8
 UniProt Protein Name    26S proteasome regulatory subunit 8
 UniProt Synonym Protein Names   
26S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; Thyroid hormone receptor-interacting protein 1; TRIP1; p45/SUG
 UniProt Gene Name    Psmc5 [Similar Products]
 UniProt Synonym Gene Names    Sug1; TRIP1 [Similar Products]
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 NCBI Summary for Psmc5    may play a role in ATP-dependent RNA/DNA unwinding [RGD, Feb 2006]
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 UniProt Comments for Psmc5    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
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 Research Articles on Psmc5    1. CaMKII-dependent phosphorylation of Rpt6 at S120 may be an important regulatory mechanism for proteasome-dependent control of synaptic remodeling in slow homeostatic plasticity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Psmc5 recombinant proteinDiseases associated with Psmc5 recombinant protein
 Products by Pathway  Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Assembly Of The Pre-replicative Complex Pathway antibodies  Assembly Of The Pre-replicative Complex Pathway Diagram
 Autodegradation Of Cdh1 By Cdh1:APC/C Pathway antibodies  Autodegradation Of Cdh1 By Cdh1:APC/C Pathway Diagram
 Autodegradation Of The E3 Ubiquitin Ligase COP1 Pathway antibodies  Autodegradation Of The E3 Ubiquitin Ligase COP1 Pathway Diagram
 CDK-mediated Phosphorylation And Removal Of Cdc6 Pathway antibodies  CDK-mediated Phosphorylation And Removal Of Cdc6 Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with Psmc5 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with Psmc5 and Brain Diseases
 Disease Models, Animal Antibodies  >1 publications with Psmc5 and Disease Models, Animal
 Liver Diseases Antibodies  >1 publications with Psmc5 and Liver Diseases
 Necrosis Antibodies  >1 publications with Psmc5 and Necrosis
Organs/Tissues associated with Psmc5 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with Psmc5 and Brain
 Liver Antibodies  >3 publications with Psmc5 and Liver
 Placenta Antibodies  >1 publications with Psmc5 and Placenta
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