NP_001013616.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
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Molecular Weight
41,384 Da
NCBI Official Full Name
26S proteasome non-ATPase regulatory subunit 4
NCBI Official Synonym Full Names
proteasome 26S subunit, non-ATPase 4
NCBI Protein Information
26S proteasome non-ATPase regulatory subunit 4
UniProt Protein Name
26S proteasome non-ATPase regulatory subunit 4
UniProt Synonym Protein Names
26S proteasome regulatory subunit RPN10
UniProt Comments for PSMD4
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains.
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Products associated with PSMD4 recombinant protein
Pathways associated with PSMD4 recombinant protein
Diseases associated with PSMD4 recombinant protein
Organs/Tissues associated with PSMD4 recombinant protein
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