Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow PAPSS1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • MMP-9 Antibody
 • S100 Calcium Binding Protein A5 (S100A5) ELISA Kit
 • Abl (Phospho-Tyr204) Antibody
 • Akt (Akt1) Antibody
 • Prostate stem cell antigen (PSCA) Recombinant Protein
 • Tryptophanyl-tRNA Synthetase, Cytoplasmic (WARS) ELISA Kit
 • ADD1 Antibody
 • Major outer membrane protein P.IB (porB) Recombinant Protein
 • ALPHA FETOPROTEIN (AFP) Purified Protein
 • NQO2 Recombinant Protein
 • family with sequence similarity 132, member B (FAM132B) ELISA Kit
 • CHD1L Antibody
 • EAPP Antibody
 • ACE (Angiotensin I Converting Enzyme) CLIA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

PAPSS1 recombinant protein :: 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS145005 PAPSS1 recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $3,515 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

3'-Phosphoadenosine 5'-Phosphosulfate Synthase 1 (PAPSS1), Recombinant Protein

 Also Known As   

Recombinant Human 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 1

 Product Synonym Names    PAPSS1 Human; 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 1 Human Recombinant
 Product Gene Name   

PAPSS1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    MGSSHHH HHH SSGLVPRGSH MGSHMR ATNV TYQAHHVSRN KRGQVVGTRG GFRGCTVWLT GLSGAGKTTV SMALEEYLVC HGIPCYTLDG DNIRQGLNKN LGFSPEDREE NVRRIAEVAK LFADAGLVCI TSFISPYTQD RNNARQIHEG ASLPFFEVFV DAPLHVCEQR DVKGLYKKAR AGEIKGFTGI DSEYEKPEAP ELVLKTDSCD VNDCVQQVVE LLQERDIVPV DASYEVKELY VPENKLHLAK TDAETLPALK INKVDMQWVQ VLAEGWATPL NGFMREREYL QCLHFDCLLD GGVINLSVPI VLTATHEDKE RLDGCTAFAL MYEGRRVAIL RNPEFFEHRK EERCARQWGT TCKNHPYIKM VMEQGDWLIG GDLQVLDRVY WNDGLDQYRL TPTELKQKFK DMNADAVFAF QLRNPVHNGH ALLMQDTHKQ LLERGYRRPV LLLHPLGGWT KDDDVPLMWR MKQHAAVLEE GVLNPETTVV AIFPSPMMYA GPTEVQWHCR ARMVAGANFY IVGRDPAGMP HPETGKDLYE PSHGAKVLTM APGLITLEIV PFRVAAYNKK KKRMDYYDSE HHEDFEFISG TRMRKLAREG QKPPEGFMAP KAWTVLTEYY KSLEKA.
 OMIM    603262
 3D Structure    ModBase 3D Structure for O43252
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    Greater than 85% as determined by SDS-PAGE.
 Form/Format    The PAPSS1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl and 20% glycerol.
Sterile Filtered colorless solution.
Section Bar
Section Bar
 Other Notes    Small volumes of PAPSS1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for PAPSS1 recombinant protein

   Description: PAPSS1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 626 amino acids (24-624) and having a molecular mass of 70.9kDa.PAPSS1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
 Product Categories/Family for PAPSS1 recombinant protein    ENZYMES; Enzymes; Synthase
NCBI/Uniprot data below describe general gene information for PAPSS1. It may not necessarily be applicable to this product.
 NCBI GI #    46094058
 NCBI GeneID    9061
 NCBI Accession #    NP_005434.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_005443.4 [Other Products]
Section Bar
 UniProt Primary Accession #    O43252 [Other Products]
 UniProt Secondary Accession #    O43841; O75332; Q96FB1; Q96TF4; Q9P1P9; Q9UE98 [Other Products]
 UniProt Related Accession #    O43252 [Other Products]
 Molecular Weight    70,833 Da
Table BarTOPTable Bar
 NCBI Official Full Name    bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
 NCBI Official Synonym Full Names    3'-phosphoadenosine 5'-phosphosulfate synthase 1
 NCBI Official Symbol    PAPSS1 [Similar Products]
 NCBI Official Synonym Symbols   
SK1; PAPSS; ATPSK1
[Similar Products]
 NCBI Protein Information    bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 1; PAPS synthase 1; PAPSS 1; SK 1; sulfurylase kinase 1
 UniProt Protein Name    Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
 UniProt Synonym Protein Names   
Sulfurylase kinase 1; SK 1; SK1
 Protein Family    Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase
 UniProt Gene Name    PAPSS1 [Similar Products]
 UniProt Synonym Gene Names    ATPSK1; PAPSS; PAPS synthase 1; PAPSS 1; SK 1; SK1; SAT [Similar Products]
 UniProt Entry Name    PAPS1_HUMAN
Section Bar
 NCBI Summary for PAPSS1    Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008]
Section Bar
 UniProt Comments for PAPSS1    PAPSS1: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.

Protein type: Kinase, other; Other Amino Acids Metabolism - selenoamino acid; Nucleotide Metabolism - purine; EC 2.7.1.25; Energy Metabolism - sulfur; EC 2.7.7.4

Chromosomal Location of Human Ortholog: 4q24

Cellular Component: cytosol

Molecular Function: adenylylsulfate kinase activity; ATP binding; sulfate adenylyltransferase (ATP) activity; nucleotidyltransferase activity

Biological Process: sulfate assimilation; glycosaminoglycan metabolic process; xenobiotic metabolic process; carbohydrate metabolic process; pathogenesis; phosphorylation; skeletal development; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Table BarTOPTable Bar
 Research Articles on PAPSS1    1. SK1 positivity and high expression were significantly associated with cancer and a shorter 5-year and overall survival.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with PAPSS1 recombinant proteinPathways associated with PAPSS1 recombinant protein
 Reference Product  PubMed Publications
 PAPSS2 recombinant protein  >12 publications with PAPSS1 and PAPSS2
 SULT1E1 recombinant protein  >3 publications with PAPSS1 and SULT1E1
 SULT1A1 recombinant protein  >1 publications with PAPSS1 and SULT1A1
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cytosolic Sulfonation Of Small Molecules Pathway antibodies  Cytosolic Sulfonation Of Small Molecules Pathway Diagram
 Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway antibodies  Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway Diagram
 Defective B3GAT3 Causes JDSSDHD Pathway antibodies  Defective B3GAT3 Causes JDSSDHD Pathway Diagram
 Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway antibodies  Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway Diagram
 Defective B4GALT7 Causes EDS, Progeroid Type Pathway antibodies  Defective B4GALT7 Causes EDS, Progeroid Type Pathway Diagram
 Defective CHST14 Causes EDS, Musculocontractural Type Pathway antibodies  Defective CHST14 Causes EDS, Musculocontractural Type Pathway Diagram
 Defective CHST3 Causes SEDCJD Pathway antibodies  Defective CHST3 Causes SEDCJD Pathway Diagram
 Defective CHST6 Causes MCDC1 Pathway antibodies  Defective CHST6 Causes MCDC1 Pathway Diagram
 Defective CHSY1 Causes TPBS Pathway antibodies  Defective CHSY1 Causes TPBS Pathway Diagram
Diseases associated with PAPSS1 recombinant proteinOrgans/Tissues associated with PAPSS1 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >1 publications with PAPSS1 and Neoplasm Metastasis
 Skin Neoplasms Antibodies  >1 publications with PAPSS1 and Skin Neoplasms
 Liver Diseases Antibodies  >1 publications with PAPSS1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with PAPSS1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with PAPSS1 and Liver Neoplasms
 Kidney Diseases Antibodies  >1 publications with PAPSS1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with PAPSS1 and Liver
 Brain Antibodies  >3 publications with PAPSS1 and Brain
 Bone Antibodies  >2 publications with PAPSS1 and Bone
 Blood Antibodies  >2 publications with PAPSS1 and Blood
 Kidney Antibodies  >2 publications with PAPSS1 and Kidney
 Heart Antibodies  >2 publications with PAPSS1 and Heart
 Skin Antibodies  >2 publications with PAPSS1 and Skin
 Adrenal Gland Antibodies  >1 publications with PAPSS1 and Adrenal Gland
 Placenta Antibodies  >1 publications with PAPSS1 and Placenta
 Embryonic Tissue Antibodies  >1 publications with PAPSS1 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions