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HMGCR recombinant protein :: 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1115221 HMGCR recombinant protein
Unit / Price
1 mg (E-Coli)  /  $3,055 +3 FREE 8GB USB
1 mg (Yeast)  /  $3,510 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), Recombinant Protein

 Also Known As   

Recombinant Strongylocentrotus purpuratus 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), partial

 Product Gene Name   

HMGCR recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-932
 Sequence    MLSRLFLAQG RFCSSHPWEV IVCTLTLTIC MLSMNYFTGL PRICGWNYEC APQVKESSLS SDVLVMCIMR TLAVAYLYLQ FTKLRTTGSK YILGIAGLFT IFSSFLFSSA VIHLFGLELT GLNEALPFFL LLIDLTKASA LTKFALSSTT QNEVVDNIAR GMAILGPTIT LDTVVTTLVI SIGTMSSIRK MEVFCCFGIL SLIANYFVFM TFFPACLSLV LELSNSNKYG RPVWHLGRFA EVLEEEEDRK PNPVVQRVKM IMRTGLVLVH AHSYWLASND TELMSRDMLY DGNLLTDKKI DPTMPLWEFY ATRLWPPTLD YILTAILATV LASHYIFFSD LATYPEKRVS IMEGHEVVNP GSDHEDASEV ETIGTLSSSP STSDVRVIES MTSRTQACQT DPVTASPRNS RSSSPVSSHS VKPARFTIGS SGSGSEDEEE EVIKEEEVEW VLETELKAPR PMPELLEILN VGKGPNALTD DEVQLLVGAK HIPAYKLENI LDNPERGVAV RRQIISKLLP ITDALEKLPY ASYDYSFVSG ACCENVIGYM PVPVGVAGPL LLDGQEFQVP MATTEGCLVA STNRGCRALR SAGGIHSVLI GDGMTRGPLV RLPSAQEAGA IKQWLEVPEN FAAIKERFES TSRFAKLKSI QTALAGRYMF LRFKALTGDA MGMNMISKGT EQALHALQTM FPNIEIMSLS GNYCTDKKVA AINWIEGRGK SVVCEATVPA HIVQQVLKTS ASALVDLNIH KNLVGSAMAG SIGGFNAHAA NIVTAIYIAT GQDAAQNIAS SNCMTLMETR GPKGGDLYLS CTMPSIELGT VGGGTVLPPQ SACLQMMDVK GSNIHGSGLN ASQLARIVCA TVMAGELSLM SALAAGHLVK SHMKHNRSAL NIASPLPSID EVATHRRSKS VDFSALKESS AAAPGTCTAN AS
 3D Structure    ModBase 3D Structure for P16393
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Strongylocentrotus purpuratus (Purple sea urchin)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of HMGCR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for HMGCR. It may not necessarily be applicable to this product.
 NCBI GI #    47551099
 NCBI GeneID    373355
 NCBI Accession #    NP_999724.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_214559.1 [Other Products]
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 UniProt Primary Accession #    P16393 [Other Products]
 UniProt Related Accession #    P16393 [Other Products]
 Molecular Weight    100,966 Da
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 NCBI Official Full Name    3-hydroxy-3-methylglutaryl-coenzyme A reductase
 NCBI Official Symbol    HMGCR [Similar Products]
 NCBI Protein Information    3-hydroxy-3-methylglutaryl-coenzyme A reductase; LOW QUALITY PROTEIN: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
 UniProt Protein Name    3-hydroxy-3-methylglutaryl-coenzyme A reductase
 UniProt Gene Name    HMGCR [Similar Products]
 UniProt Synonym Gene Names    HMG-CoA reductase [Similar Products]
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 UniProt Comments for HMGCR    This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HMGCR recombinant proteinPathways associated with HMGCR recombinant protein
 Reference Product  PubMed Publications
 CYP51 recombinant protein  >6 publications with HMGCR and CYP51
 Products by Pathway  Pathway Diagram
 C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies  C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
 C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies  C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
 Terpenoid Backbone Biosynthesis Pathway antibodies  Terpenoid Backbone Biosynthesis Pathway Diagram
 Terpenoid Backbone Biosynthesis Pathway antibodies  Terpenoid Backbone Biosynthesis Pathway Diagram
Diseases associated with HMGCR recombinant proteinOrgans/Tissues associated with HMGCR recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >44 publications with HMGCR and Cardiovascular Diseases
 Neoplasms Antibodies  >41 publications with HMGCR and Neoplasms
 Dyslipidemias Antibodies  >34 publications with HMGCR and Dyslipidemias
 Fatty Liver Antibodies  >33 publications with HMGCR and Fatty Liver
 Atherosclerosis Antibodies  >33 publications with HMGCR and Atherosclerosis
 Hypercholesterolemia Antibodies  >32 publications with HMGCR and Hypercholesterolemia
 Hyperlipidemias Antibodies  >29 publications with HMGCR and Hyperlipidemias
 Nervous System Diseases Antibodies  >28 publications with HMGCR and Nervous System Diseases
 Liver Diseases Antibodies  >24 publications with HMGCR and Liver Diseases
 Heart Diseases Antibodies  >22 publications with HMGCR and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Embryo Antibodies  >11 publications with HMGCR and Embryo
 Larval Antibodies  >2 publications with HMGCR and Larval
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