NP_055177.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,012 Da
NCBI Official Full Name
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform 1
NCBI Official Synonym Full Names
3-hydroxyisobutyryl-CoA hydrolase
NCBI Official Synonym Symbols
NCBI Protein Information
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
UniProt Protein Name
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
UniProt Synonym Protein Names
3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H
UniProt Synonym Gene Names
NCBI Summary for HIBCH
This gene encodes the enzyme responsible for hydrolysis of both HIBYL-CoA and beta-hydroxypropionyl-CoA. Mutations in this gene have been associated with 3-hyroxyisobutyryl-CoA hydrolase deficiency. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
UniProt Comments for HIBCH
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
Research Articles on HIBCH
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Products associated with HIBCH recombinant protein
Pathways associated with HIBCH recombinant protein
Diseases associated with HIBCH recombinant protein
Organs/Tissues associated with HIBCH recombinant protein
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