XP_001880429.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
predicted protein
NCBI Protein Information
hypothetical protein
UniProt Protein Name
Very-long-chain 3-oxoacyl-CoA reductase
UniProt Synonym Protein Names
3-ketoacyl-CoA reductase; 3-ketoreductase; KAR; Microsomal beta-keto-reductase
UniProt Synonym Gene Names
UniProt Entry Name
MKAR_LACBS
UniProt Comments for LACBIDRAFT_192627
Function: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids
By similarity. HAMAP-Rule MF_03107
Catalytic activity: A very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain 3-oxoacyl-CoA + NADPH. HAMAP-Rule MF_03107
Subcellular location: Endoplasmic reticulum membrane
By similarity; Single-pass membrane protein
Potential HAMAP-Rule MF_03107.
Sequence similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
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Pathways associated with LACBIDRAFT_192627 recombinant protein
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