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Abat recombinant protein :: 4-aminobutyrate aminotransferase, mitochondrial (Abat) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS952908 Abat recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $895 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,105 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,195 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,320 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,320 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,355 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,400 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,490 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,875 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,010 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,045 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,270 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,645 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

4-aminobutyrate aminotransferase, mitochondrial (Abat), Recombinant Protein

 Also Known As   

Recombinant Rat 4-aminobutyrate aminotransferase, mitochondrial (Abat)

 Product Gene Name   

Abat recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    28-500aa, Full Length of Mature Protein
 Sequence    ISQAAAKVDF EFDYDGPLMK TEVPGPRSQE LMKQLNTIQN AEAVHFFCNY EESRGNYLVD VDGNRMLDLY SQISSVPIGY NHPALAKLVQ QPQNASTFIN RPALGILPPE NFVDKLRESL MSVAPKGMCQ LITMACGSCS NENAFKTIFM WYRSKERGQR GFSKEELETC MVNQSPGCPD YSILSFMGAF HGRTMGCLAT THSKAIHKID IPSFDWPIAP FPRLKYPLEE FVTDNQQEEA RCLEEVEDLI VKYRKKKRTV AGIIVEPIQS EGGDNHASDD FFRKLRDIAR KHGCAFLVDE VQTGGGCTGK FWAHEHWGLD DPADVMSFSK KMMTGGFFHK EEFRPSAPYR IFNTWLGDPS KNLLLAEVIN IIKREDLLNN VAHAGKTLLT GLLDLQAQYP QFVSRVRGRG TFCSFDTPDE AIRNKLILIA RNKGVVLGGC GDKSIRFRPT LVFRDHHAHL FLNIFSGILA DFK
 3D Structure    ModBase 3D Structure for P50554
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Abat recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Abat recombinant protein

   4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
NCBI/Uniprot data below describe general gene information for Abat. It may not necessarily be applicable to this product.
 NCBI GI #    13591900
 NCBI GeneID    81632
 NCBI Accession #    NP_112265.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_031003.2 [Other Products]
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 UniProt Primary Accession #    P50554 [Other Products]
 UniProt Secondary Accession #    O70539; Q66HM1 [Other Products]
 UniProt Related Accession #    P50554 [Other Products]
 Molecular Weight    56,456 Da
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 NCBI Official Full Name    4-aminobutyrate aminotransferase, mitochondrial
 NCBI Official Synonym Full Names    4-aminobutyrate aminotransferase
 NCBI Official Symbol    Abat [Similar Products]
 NCBI Official Synonym Symbols   
Gabat; beta-AlaAT
[Similar Products]
 NCBI Protein Information    4-aminobutyrate aminotransferase, mitochondrial
 UniProt Protein Name    4-aminobutyrate aminotransferase, mitochondrial
 UniProt Synonym Protein Names   
(S)-3-amino-2-methylpropionate transaminase (EC:2.6.1.22); GABA aminotransferase; GABA-AT
 UniProt Gene Name    Abat [Similar Products]
 UniProt Synonym Gene Names    Gabat; GABA-AT; GABA transaminase; GABA-T [Similar Products]
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 NCBI Summary for Abat    main component of the 4-aminobutyrate (GABA) shunt; major inhibitory neurotransmitter [RGD, Feb 2006]
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 UniProt Comments for Abat    Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
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 Research Articles on Abat    1. Daytime restricted feeding influences the daily variations of GABA-T mRNA levels, stability, and catalytic activity of GABA-T.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Abat recombinant proteinPathways associated with Abat recombinant protein
 Reference Product  PubMed Publications
 Gad2 recombinant protein  >1 publications with Abat and Gad2
 Aldh5a1 recombinant protein  >1 publications with Abat and Aldh5a1
 Gad1 recombinant protein  >1 publications with Abat and Gad1
 Products by Pathway  Pathway Diagram
 Alanine And Aspartate Metabolism Pathway antibodies  Alanine And Aspartate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 GABA (gamma-Aminobutyrate) Shunt Pathway antibodies  GABA (gamma-Aminobutyrate) Shunt Pathway Diagram
 GABA (gamma-Aminobutyrate) Shunt Pathway antibodies  GABA (gamma-Aminobutyrate) Shunt Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 Propanoate Metabolism Pathway antibodies  Propanoate Metabolism Pathway Diagram
Diseases associated with Abat recombinant proteinOrgans/Tissues associated with Abat recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with Abat and Nervous System Diseases
 Mental Disorders Antibodies  >5 publications with Abat and Mental Disorders
 Pain Antibodies  >4 publications with Abat and Pain
 Drug Toxicity Antibodies  >3 publications with Abat and Drug Toxicity
 Brain Diseases Antibodies  >3 publications with Abat and Brain Diseases
 Genetic Predisposition to Disease Antibodies  >3 publications with Abat and Genetic Predisposition to Disease
 Cholestasis Antibodies  >2 publications with Abat and Cholestasis
 Immune System Diseases Antibodies  >2 publications with Abat and Immune System Diseases
 Epilepsy Antibodies  >2 publications with Abat and Epilepsy
 Movement Disorders Antibodies  >2 publications with Abat and Movement Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with Abat and Brain
 Liver Antibodies  >4 publications with Abat and Liver
 Kidney Antibodies  >1 publications with Abat and Kidney
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