NP_188761.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
60,842 Da
NCBI Official Full Name
4-coumarate:CoA ligase 2
NCBI Official Synonym Symbols
4-COUMARATE:COA LIGASE; 4-coumarate:CoA ligase 2; AT4CL2 [Similar Products]
NCBI Protein Information
4-coumarate:CoA ligase 2
UniProt Protein Name
4-coumarate--CoA ligase 2
UniProt Synonym Protein Names
4-coumarate--CoA ligase isoform 2; At4CL2; 4-coumaroyl-CoA synthase 2
UniProt Synonym Gene Names
NCBI Summary for 4CL2
encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, 5-OH-ferulic acid and cinnamic acid. At4CL2 was unable to use sinapic acid as substrate.
UniProt Comments for 4CL2
Produces CoA thioesters of a variety of hydroxy- and methoxy-substituted cinnamic acids, which are used to synthesize several phenylpropanoid-derived compounds, including anthocyanins, flavonoids, isoflavonoids, coumarins, lignin, suberin and wall-bound phenolics.
Research Articles on 4CL2
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Pathways associated with 4CL2 recombinant protein
Products by Pathway |
Pathway Diagram |
4-hydroxybenzoate Biosynthesis I (animals) Pathway antibodies |
4-hydroxybenzoate Biosynthesis I (animals) Pathway Diagram |
4-hydroxybenzoate Biosynthesis V Pathway antibodies |
4-hydroxybenzoate Biosynthesis V Pathway Diagram |
Biosynthesis Of Secondary Metabolites Pathway antibodies |
Biosynthesis Of Secondary Metabolites Pathway Diagram |
Capsaicin Biosynthesis, L-Phenylalanine => Capsaicin Pathway antibodies |
Capsaicin Biosynthesis, L-Phenylalanine => Capsaicin Pathway Diagram |
Capsaicin Biosynthesis, L-Phenylalanine => Capsaicin Pathway antibodies |
Capsaicin Biosynthesis, L-Phenylalanine => Capsaicin Pathway Diagram |
Flavanone Biosynthesis, Phenylalanine => Naringenin Pathway antibodies |
Flavanone Biosynthesis, Phenylalanine => Naringenin Pathway Diagram |
Flavanone Biosynthesis, Phenylalanine => Naringenin Pathway antibodies |
Flavanone Biosynthesis, Phenylalanine => Naringenin Pathway Diagram |
Metabolic Pathways antibodies |
Metabolic Pathways Diagram |
Monolignol Biosynthesis, Phenylalanine/tyrosine => Monolignol Pathway antibodies |
Monolignol Biosynthesis, Phenylalanine/tyrosine => Monolignol Pathway Diagram |
Monolignol Biosynthesis, Phenylalanine/tyrosine => Monolignol Pathway antibodies |
Monolignol Biosynthesis, Phenylalanine/tyrosine => Monolignol Pathway Diagram |
Organs/Tissues associated with 4CL2 recombinant protein
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