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PRO2640 recombinant protein :: 40S ribosomal protein S14 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS717098
SDS-PAGE
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $285 +1 FREE 8GB USB
0.2 mg  /  $460 +1 FREE 8GB USB
0.5 mg  /  $750 +1 FREE 8GB USB
1 mg  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

40S ribosomal protein S14 (PRO2640), Recombinant Protein

 Also Known As   

Recombinant Human 40S ribosomal protein S14

 Product Gene Name   

PRO2640 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-146aa; Partial
 Sequence    APRKGKEKKE EQVISLGPQV AEGENVFGVC HIFASFNDTF VHVTDLSGKE TICRVTGGMK VKADRDESSP YAAMLAAQDV AQRCKELGIT ALHIKLRATG GNRTKTPGPG AQSALRALAR SGMKIGRIED VTPIPSDSTR RKGGR
 OMIM    130620
 3D Structure    ModBase 3D Structure for P62263
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PRO2640 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 SDS-PAGE of PRO2640 recombinant protein    PRO2640 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for PRO2640. It may not necessarily be applicable to this product.
 NCBI GI #    68160915
 NCBI GeneID    6208
 NCBI Accession #    NP_001020241.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001025070.1 [Other Products]
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 UniProt Primary Accession #    P62263 [Other Products]
 UniProt Secondary Accession #    P06366; Q5BJI0; B2R5G5; D3DQG5 [Other Products]
 UniProt Related Accession #    P62263 [Other Products]
 Molecular Weight    42.9kD
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 NCBI Official Full Name    40S ribosomal protein S14
 NCBI Official Synonym Full Names    ribosomal protein S14
 NCBI Official Symbol    RPS14 [Similar Products]
 NCBI Official Synonym Symbols   
S14; EMTB
[Similar Products]
 NCBI Protein Information    40S ribosomal protein S14
 UniProt Protein Name    40S ribosomal protein S14
 Protein Family    40S ribosomal protein
 UniProt Gene Name    RPS14 [Similar Products]
 UniProt Entry Name    RS14_HUMAN
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 NCBI Summary for PRO2640    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PRO2640    RPS14: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Translation; Ribosomal; RNA-binding

Chromosomal Location of Human Ortholog: 5q31-q33

Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; mitochondrion; nucleolus

Molecular Function: mRNA 5'-UTR binding; protein binding; RNA binding; structural constituent of ribosome; translation regulator activity

Biological Process: cellular protein metabolic process; erythrocyte differentiation; gene expression; maturation of SSU-rRNA; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); mRNA catabolic process, nonsense-mediated decay; negative regulation of transcription from RNA polymerase II promoter; regulation of translation; ribosomal small subunit assembly and maintenance; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription

Disease: Chromosome 5q Deletion Syndrome
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Product References and Citations for PRO2640 recombinant protein

   Homologous ribosomal proteins in bacteria, yeast, and humans.Chen I.-T., Dixit A., Rhoads D.D., Roufa D.J.Proc. Natl. Acad. Sci. U.S.A. 83:6907-6911(1986) Primary structure of human ribosomal protein S14 and the gene that encodes it.Rhoads D.D., Dixit A., Roufa D.J.Mol. Cell. Biol. 6:2774-2783(1986) Functional prediction of the coding sequences of 121 new genes deduced by analysis of cDNA clones from human fetal liver.Zhang C., Yu Y., Zhang S., Wei H., Zhou G., Ouyang S., Luo L., Bi J., Liu M., He F. Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004)
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 Research Articles on PRO2640    1. Partial silencing of RPS14 inhibits the proliferation of SKM-1, an acute myeloid leukemia cell line, and RPS14 negatively regulates p53 activation in SKM-1 cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PRO2640 recombinant proteinPathways associated with PRO2640 recombinant protein
 Reference Product  PubMed Publications
 RPS19 recombinant protein  >14 publications with PRO2640 and RPS19
 RPS3 recombinant protein  >8 publications with PRO2640 and RPS3
 RPS8 recombinant protein  >7 publications with PRO2640 and RPS8
 RPS5 recombinant protein  >5 publications with PRO2640 and RPS5
 RPS29 recombinant protein  >3 publications with PRO2640 and RPS29
 RPS11 recombinant protein  >3 publications with PRO2640 and RPS11
 RPS16 recombinant protein  >3 publications with PRO2640 and RPS16
 RPS13 recombinant protein  >2 publications with PRO2640 and RPS13
 RPS28 recombinant protein  >2 publications with PRO2640 and RPS28
 RPS15A recombinant protein  >1 publications with PRO2640 and RPS15A
 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytoplasmic Ribosomal Proteins Pathway antibodies  Cytoplasmic Ribosomal Proteins Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Eukaryotic Translation Termination Pathway antibodies  Eukaryotic Translation Termination Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies  Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
Diseases associated with PRO2640 recombinant proteinOrgans/Tissues associated with PRO2640 recombinant protein
 Disease Name  Pubmed Publications
 Chromosome 5q Deletion Syndrome Antibodies  >17 publications with PRO2640 and Chromosome 5q Deletion Syndrome
 Disease Models, Animal Antibodies  >5 publications with PRO2640 and Disease Models, Animal
 Neurobehavioral Manifestations Antibodies  >2 publications with PRO2640 and Neurobehavioral Manifestations
 Carcinoma Antibodies  >2 publications with PRO2640 and Carcinoma
 Abnormalities, Drug-Induced Antibodies  >1 publications with PRO2640 and Abnormalities, Drug-Induced
 Liver Neoplasms Antibodies  >1 publications with PRO2640 and Liver Neoplasms
 Lung Diseases Antibodies  >1 publications with PRO2640 and Lung Diseases
 Liver Diseases Antibodies  >1 publications with PRO2640 and Liver Diseases
 Urinary Bladder Neoplasms Antibodies  >1 publications with PRO2640 and Urinary Bladder Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with PRO2640 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >24 publications with PRO2640 and Bone
 Bone Marrow Antibodies  >24 publications with PRO2640 and Bone Marrow
 Blood Antibodies  >20 publications with PRO2640 and Blood
 Ovary Antibodies  >6 publications with PRO2640 and Ovary
 Brain Antibodies  >3 publications with PRO2640 and Brain
 Heart Antibodies  >3 publications with PRO2640 and Heart
 Mammary Gland Antibodies  >1 publications with PRO2640 and Mammary Gland
 Liver Antibodies  >1 publications with PRO2640 and Liver
 Skin Antibodies  >1 publications with PRO2640 and Skin
 Lung Antibodies  >1 publications with PRO2640 and Lung
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