NP_001013.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
16,060 Da
NCBI Official Full Name
40S ribosomal protein S19 isoform 1
NCBI Official Synonym Full Names
ribosomal protein S19
NCBI Protein Information
40S ribosomal protein S19
UniProt Protein Name
40S ribosomal protein S19
UniProt Synonym Protein Names
Small ribosomal subunit protein eS19
NCBI Summary for RPS19
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Comments for RPS19
Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
Research Articles on RPS19
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Products associated with RPS19 recombinant protein
Pathways associated with RPS19 recombinant protein
Diseases associated with RPS19 recombinant protein
Organs/Tissues associated with RPS19 recombinant protein
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