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Rpsa recombinant protein :: 40S ribosomal protein SA (Rpsa) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS965572 Rpsa recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $700 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $830 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $940 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $975 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,030 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,115 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,210 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,225 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,260 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,460 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,765 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,840 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,915 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,350 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

40S ribosomal protein SA (Rpsa), Recombinant Protein

 Also Known As   

Recombinant Mouse 40S ribosomal protein SA (Rpsa)

 Product Synonym Names    40S ribosomal protein SA; 37 kDa laminin receptor precursor; 37LRP; 37 kDa oncofetal antigen; 37/67 kDa laminin receptor; LRP/LR; 67 kDa laminin receptor; 67LR; Laminin receptor 1; LamR; Laminin-binding protein precursor p40; LBP/p40; OFA/iLRP
 Product Gene Name   

Rpsa recombinant protein

[Similar Products]
 Product Synonym Gene Name    Rpsa; Lamr1; P40-8 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-295aa; Full length protein
 Sequence    SGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA GRFTPGTFTN QIQAAFREPR LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR EVLRMRGTIS REHPWEVMPD LYFYRDPEEI EKEEQAAAEK AVTKEEFQGE WTAPAPEFTA AQPEVADWSE GVQVPSVPIQ QFPTEDWSAQ PATEDWSAAP TAQATEWVGA TTEWS
 3D Structure    ModBase 3D Structure for P14206
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Rpsa recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Rpsa recombinant protein

   Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
NCBI/Uniprot data below describe general gene information for Rpsa. It may not necessarily be applicable to this product.
 NCBI GI #    224994260
 NCBI GeneID    16785
 NCBI Accession #    NP_035159.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_011029.4 [Other Products]
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 UniProt Primary Accession #    P14206 [Other Products]
 UniProt Secondary Accession #    Q58E74; Q8BHL0; Q8BNL2; Q91V31; Q9CY13 [Other Products]
 UniProt Related Accession #    P14206 [Other Products]
 Molecular Weight    32,838 Da
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 NCBI Official Full Name    40S ribosomal protein SA
 NCBI Official Synonym Full Names    ribosomal protein SA
 NCBI Official Symbol    Rpsa [Similar Products]
 NCBI Official Synonym Symbols   
MLR; P40; 67lr; Lamr; 67kDa; Lamr1; P40-3; P40-8; Lamrl1; AL022858
[Similar Products]
 NCBI Protein Information    40S ribosomal protein SA; 37LRP; LRP/LR; LBP/p40; OFA/iLRP; P40-3, functional; P40-8, functional; 37 kDa laminin receptor; 67 kDa laminin receptor; 37 kDa oncofetal antigen; 37/67 kDa laminin receptor; laminin-binding protein precursor p40; laminin receptor 1 (67kD, ribosomal protein SA)
 UniProt Protein Name    40S ribosomal protein SA
 UniProt Synonym Protein Names   
37 kDa laminin receptor precursor; 37 kDa oncofetal antigen37/67 kDa laminin receptor; 67 kDa laminin receptor; Laminin receptor 1; Laminin-binding protein precursor p40
 Protein Family    30S ribosomal protein
 UniProt Gene Name    Rpsa [Similar Products]
 UniProt Synonym Gene Names    LBP/p40 [Similar Products]
 UniProt Entry Name    RSSA_MOUSE
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 UniProt Comments for Rpsa    RPSA: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Belongs to the ribosomal protein S2P family.

Protein type: Ribosomal

Cellular Component: extracellular matrix; small ribosomal subunit; cell soma; membrane; cytoplasm; plasma membrane; basement membrane; ribosome; intracellular; ribonucleoprotein complex; nucleus; cytosol

Molecular Function: structural constituent of ribosome; laminin receptor activity; laminin binding; ribosome binding

Biological Process: rRNA export from nucleus; cell-cell adhesion; translation; endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal small subunit assembly and maintenance; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
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 Research Articles on Rpsa    1. a high plasticity of RPSA, which could be important for its multiple cellular localizations and functional interactions
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Rpsa recombinant proteinDiseases associated with Rpsa recombinant protein
 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytoplasmic Ribosomal Proteins Pathway antibodies  Cytoplasmic Ribosomal Proteins Pathway Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Eukaryotic Translation Termination Pathway antibodies  Eukaryotic Translation Termination Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies  Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >7 publications with Rpsa and Carcinoma
 Adenocarcinoma Antibodies  >4 publications with Rpsa and Adenocarcinoma
 Brain Diseases Antibodies  >4 publications with Rpsa and Brain Diseases
 Disease Models, Animal Antibodies  >3 publications with Rpsa and Disease Models, Animal
 Liver Neoplasms Antibodies  >3 publications with Rpsa and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >3 publications with Rpsa and Cardiovascular Diseases
 Prostatic Diseases Antibodies  >3 publications with Rpsa and Prostatic Diseases
 Liver Diseases Antibodies  >2 publications with Rpsa and Liver Diseases
 Neoplasms, Experimental Antibodies  >2 publications with Rpsa and Neoplasms, Experimental
 Carcinoma, Hepatocellular Antibodies  >2 publications with Rpsa and Carcinoma, Hepatocellular
Organs/Tissues associated with Rpsa recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >11 publications with Rpsa and Blood
 Brain Antibodies  >5 publications with Rpsa and Brain
 Liver Antibodies  >4 publications with Rpsa and Liver
 Spleen Antibodies  >3 publications with Rpsa and Spleen
 Heart Antibodies  >2 publications with Rpsa and Heart
 Eye Antibodies  >2 publications with Rpsa and Eye
 Lung Antibodies  >2 publications with Rpsa and Lung
 Skin Antibodies  >2 publications with Rpsa and Skin
 Joint Antibodies  >2 publications with Rpsa and Joint
 Testis Antibodies  >1 publications with Rpsa and Testis
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