NP_892042.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
30,209 Da
NCBI Official Full Name
5'-AMP-activated protein kinase subunit beta-2
NCBI Official Synonym Full Names
protein kinase, AMP-activated, beta 2 non-catalytic subunit
NCBI Official Synonym Symbols
AW049591; BB124140; 5730553K21Rik [Similar Products]
NCBI Protein Information
5'-AMP-activated protein kinase subunit beta-2
UniProt Protein Name
5'-AMP-activated protein kinase subunit beta-2
UniProt Synonym Gene Names
UniProt Comments for Prkab2
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) ().
Research Articles on Prkab2
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Products associated with Prkab2 recombinant protein
Pathways associated with Prkab2 recombinant protein
Diseases associated with Prkab2 recombinant protein
Organs/Tissues associated with Prkab2 recombinant protein
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