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5-HT1B recombinant protein :: 5-hydroxytryptamine receptor 2B (5-HT1B) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1064192 5-HT1B recombinant protein
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

5-hydroxytryptamine receptor 2B (5-HT1B), Recombinant Protein

 Also Known As   

Recombinant Drosophila melanogaster 5-hydroxytryptamine receptor 2B (5-HT1B)

 Product Synonym Names    Recombinant 5-hydroxytryptamine receptor 2B (5-HT1B); 5-hydroxytryptamine receptor 2B; 5-HT receptor 2B; 5-hydroxytryptamine receptor 1B; 5-HT receptor 1B Serotonin receptor 1B Serotonin receptor 2B
 Product Gene Name   

5-HT1B recombinant protein

[Similar Products]
 Product Synonym Gene Name    5-HT1B; 5HT-R2B; CG15113 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-617
 Sequence    MLKTVTTAMA AGDDDVPASI LEIELPAILL NESLFIELNG NLTQLVDTTS NLSQIVWNRS INGNGNSNTF DLVDDEQERA AVEFWLLVKM IAMAVVLGLM ILVTIIGNVF VIAAIILERN LQNVANYLVA SLAVADLFVA CLVMPLGAVY EISNGWILGP ELCDIWTSCD VLCCTASILH LVAIAADRYW TVTNIDYNNL RTPRRVFLMI FCVWFAALIV SLAPQFGWKD PDYMKRIEEQ HCMVSQDVGY QIFATCCTFY VPLLVILFLY WKIYIIARKR IQRRAQKSFN VTLTETDCDS AVRELKKERS KRRAERKRLE AGERTPVDGD GTGGQLQRRT RKRMRICFGR NTNTANVVAG SEGAVARSMA AIAVDFASLA ITREETEFST SNYDNKSHAG TELTTVSSDA DDYRTSNANE IITLSQQVAH ATQHHLIASH LNAITPLAQS IAMGGVGCLT TTTPSEKALS GAGTVAGAVA GGSGSGSGEE GAGTEGKNAG VGLGGVLASI ANPHQKLAKR RQLLEAKRER KAAQTLAIIT GAFVICWLPF FVMALTMSLC KECEIHTAVA SLFLWLGYFN STLNPVIYTI FNPEFRRAFK RILFGRKAAA RARSAKI
 Chromosome Location    Chromosome: 2R; NT_033778.3 (14909830..14920128, complement). Location: 56B1-56B1
 3D Structure    ModBase 3D Structure for P28286
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Drosophila melanogaster (Fruit fly)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of 5-HT1B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for 5-HT1B. It may not necessarily be applicable to this product.
 NCBI GI #    78707343
 NCBI GeneID    37191
 NCBI Accession #    NP_523789.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_079065.4 [Other Products]
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 UniProt Primary Accession #    P28286 [Other Products]
 UniProt Secondary Accession #    Q059D0; Q5MRS0; Q5MRY0; Q5MS20; Q5MS32; Q5MS65; Q5MS79; Q5MS95; A8E6N2; B7YZK9; C0PV72 [Other Products]
 UniProt Related Accession #    P28286 [Other Products]
 Molecular Weight    67,530 Da [Similar Products]
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 NCBI Official Full Name    serotonin receptor 1B, isoform A
 NCBI Official Synonym Full Names    Serotonin receptor 1B
 NCBI Official Symbol    5-HT1B [Similar Products]
 NCBI Official Synonym Symbols   
5-HT-dro2B; 5-HT1BDro; 5-HT[1B]Dro; 5-HT[[1BDro]]; 5-HT[[dro2B]]; 5HT-dro2B; 5HT-dro[[2B]]; 5HT-R2B; 5HT1B; 5htdro2b; CG15113; CG30126; d5-HT1B; Dm5HTdro2B; DmelCG15113; DRO2B
[Similar Products]
 NCBI Protein Information    CG15113 gene product from transcript CG15113-RC; 5-HT1B-PA; 5-HT1B-PC; CG15113-PA; CG15113-PC; drosophila serotonin receptor 1B; serotonin receptor 2B
 UniProt Protein Name    5-hydroxytryptamine receptor 2B
 UniProt Synonym Protein Names   
5-hydroxytryptamine receptor 1B; 5-HT receptor 1B; Serotonin receptor 1B; Serotonin receptor 2B
 UniProt Gene Name    5-HT1B [Similar Products]
 UniProt Synonym Gene Names    5HT-R2B; 5-HT receptor 2B [Similar Products]
 UniProt Entry Name    5HT2B_DROME
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 UniProt Comments for 5-HT1B    Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Sequence caution: The sequence AAS74713.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence ABV82206.1 differs from that shown. Reason: Intron retention.The sequence CAA77571.1 differs from that shown. Reason: Chimeric DNA sequence.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with 5-HT1B recombinant proteinDiseases associated with 5-HT1B recombinant protein
 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Serotonin Receptors Pathway antibodies  Serotonin Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Disease Name  Pubmed Publications
 Cocaine-Related Disorders Antibodies  >18 publications with 5-HT1B and Cocaine-Related Disorders
 Dyskinesia, Drug-Induced Antibodies  >11 publications with 5-HT1B and Dyskinesia, Drug-Induced
 Necrosis Antibodies  >4 publications with 5-HT1B and Necrosis
 Hyperkinesis Antibodies  >4 publications with 5-HT1B and Hyperkinesis
 Poland Syndrome Antibodies  >3 publications with 5-HT1B and Poland Syndrome
 Intracranial Arterial Diseases Antibodies  >1 publications with 5-HT1B and Intracranial Arterial Diseases
 Neoplasms, Fibrous Tissue Antibodies  >1 publications with 5-HT1B and Neoplasms, Fibrous Tissue
Organs/Tissues associated with 5-HT1B recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Whole Body Antibodies  >5 publications with 5-HT1B and Whole Body
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