NP_075227.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,428 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 7
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
NCBI Official Synonym Symbols
NCBI Protein Information
5-hydroxytryptamine receptor 7
UniProt Protein Name
5-hydroxytryptamine receptor 7
UniProt Synonym Protein Names
5-HT-X; GPRFO; Serotonin receptor 7
UniProt Synonym Gene Names
UniProt Entry Name
5HT7R_RAT
NCBI Summary for Htr7
receptor for 5-hydroxytryptamine; involved in modulatory action on cerebellar function [RGD, Feb 2006]
UniProt Comments for Htr7
5-HT(7): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: cell soma; dendrite; integral to membrane; integral to plasma membrane; nerve terminal; plasma membrane; rough endoplasmic reticulum; synaptic vesicle
Molecular Function: neurotransmitter receptor activity; serotonin receptor activity
Biological Process: behavioral response to pain; circadian rhythm; detection of mechanical stimulus involved in sensory perception of pain; G-protein signaling, coupled to cyclic nucleotide second messenger; memory; micturition; negative regulation of circadian sleep/wake cycle, REM sleep; negative regulation of serotonin secretion; response to corticosterone stimulus; response to electrical stimulus; serotonin receptor signaling pathway; serotonin receptor, adenylate cyclase activating pathway; smooth muscle contraction; synaptic transmission; urinary bladder smooth muscle contraction; vasoconstriction
Research Articles on Htr7
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Pathways associated with Htr7 recombinant protein
Diseases associated with Htr7 recombinant protein
Organs/Tissues associated with Htr7 recombinant protein
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