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Add To Compare List OASL recombinant protein :: 59 kDa 2'-5'-oligoadenylate synthase-like protein (OASL) Recombinant Protein Catalog # MBS1460772 Unit / Price 0.02 mg (E-Coli) / $290 +1 FREE 8GB USB 0.1 mg (E-Coli) / $470 +1 FREE 8GB USB 0.02 mg (Yeast) / $1,145 +1 FREE 8GB USB 0.1 mg (Yeast) / $1,340 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,385 +1 FREE 8GB USB 1 mg (E-Coli) / $1,625 +2 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,650 +2 FREE 8GB USB 0.1 mg (Baculovirus) / $1,985 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,585 +3 FREE 8GB USB 1 mg (Yeast) / $2,660 +3 FREE 8GB USB 1 mg (Baculovirus) / $3,840 +4 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $6,265 +7 FREE 8GB USB 5x1 mg (E-Coli) / $7,140 +8 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name 59 kDa 2'-5'-oligoadenylate synthase-like protein (OASL), Recombinant Protein Full Product Name Recombinant Human 59 kDa 2'-5'-oligoadenylate synthase-like protein (OASL) Product Gene Name OASL recombinant protein[Similar Products] Product Synonym Gene Name OASL[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 2-514, Full length protein Sequence ALMQELYSTP ASRLDSFVAQ WLQPHREWKE EVLDAVRTVE EFLRQEHFQG KRGLDQDVRV LKVVKVGSFG NGTVLRSTRE VELVAFLSCF HSFQEAAKHH KDVLRLIWKT MWQSQDLLDL GLEDLRMEQR VPDALVFTIQ TRGTAEPITV TIVPAYRALG PSLPNSQPPP EVYVSLIKAC GGPGNFCPSF SELQRNFVKH RPTKLKSLLR LVKHWYQQYV KARSPRANLP PLYALELLTI YAWEMGTEED ENFMLDEGFT TVMDLLLEYE VICIYWTKYY TLHNAIIEDC VRKQLKKERP IILDPADPTL NVAEGYRWDI VAQRASQCLK QDCCYDNREN PISSWNVKRA RDIHLTVEQR GYPDFNLIVN PYEPIRKVKE KIRRTRGYSG LQRLSFQVPG SERQLLSSRC SLAKYGIFSH THIYLLETIP SEIQVFVKNP DGGSYAYAIN PNSFILGLKQ QIEDQQGLPK KQQQLEFQGQ VLQDWLGLGI YGIQDSDTLI LSKKKGEALF PAS OMIM 603281 3D Structure ModBase 3D Structure for Q15646 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Human Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of OASL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP NCBI/Uniprot data below describe general gene information for OASL. It may not necessarily be applicable to this product. NCBI GI # 387849330 NCBI GeneID 8638 NCBI Accession # NP_001248754.1 [Other Products] NCBI GenBank Nucleotide # NM_001261825.1 [Other Products] UniProt Primary Accession # Q15646 [Other Products] UniProt Secondary Accession # O75686; Q17R95; Q9Y6K6; Q9Y6K7; B2RAZ2; I1YDD2[Other Products] UniProt Related Accession # Q15646[Other Products] Molecular Weight 43,942 Da TOP NCBI Official Full Name 2'-5'-oligoadenylate synthase-like protein isoform c NCBI Official Synonym Full Names 2'-5'-oligoadenylate synthetase like NCBI Official Symbol OASL [Similar Products] NCBI Official Synonym Symbols OASL1; OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL [Similar Products] NCBI Protein Information 2'-5'-oligoadenylate synthase-like protein UniProt Protein Name 2'-5'-oligoadenylate synthase-like protein UniProt Synonym Protein Names 2'-5'-OAS-related protein; 2'-5'-OAS-RP; 59 kDa 2'-5'-oligoadenylate synthase-like protein; Thyroid receptor-interacting protein 14; TR-interacting protein 14; TRIP-14; p59 OASL; p59OASL Protein Family 2'-5'-oligoadenylate synthase-like protein UniProt Gene Name OASL [Similar Products] UniProt Synonym Gene Names TRIP14; 2'-5'-OAS-RP; TR-interacting protein 14; TRIP-14; p59OASL [Similar Products] TOP TOP UniProt Comments for OASL Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. Research Articles on OASL 1. These data uncover a promycobacterial role for STING-dependent OASL production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with OASL recombinant protein Reference Product PubMed Publications MX1 recombinant protein >13 publications with OASL and MX1 ISG15 recombinant protein >11 publications with OASL and ISG15 IRF7 recombinant protein >8 publications with OASL and IRF7 IFIT1 recombinant protein >7 publications with OASL and IFIT1 IFIT2 recombinant protein >4 publications with OASL and IFIT2 IFIT3 recombinant protein >3 publications with OASL and IFIT3 ISG20 recombinant protein >2 publications with OASL and ISG20 RNASEL recombinant protein >2 publications with OASL and RNASEL MX2 recombinant protein >1 publications with OASL and MX2 Pathways associated with OASL recombinant protein Products by Pathway Pathway Diagram Cytokine Signaling In Immune System Pathway antibodies Cytokine Signaling In Immune System Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Interferon Signaling Pathway antibodies Interferon Signaling Pathway Diagram Interferon Alpha/beta Signaling Pathway antibodies Interferon Alpha/beta Signaling Pathway Diagram Interferon Gamma Signaling Pathway antibodies Interferon Gamma Signaling Pathway Diagram Diseases associated with OASL recombinant protein Disease Name Pubmed Publications Nervous System Diseases Antibodies >9 publications with OASL and Nervous System Diseases Inflammation Antibodies >4 publications with OASL and Inflammation Influenza, Human Antibodies >3 publications with OASL and Influenza, Human Necrosis Antibodies >2 publications with OASL and Necrosis Hypertension Antibodies >1 publications with OASL and Hypertension Heart Diseases Antibodies >1 publications with OASL and Heart Diseases Kidney Diseases Antibodies >1 publications with OASL and Kidney Diseases Proteinuria Antibodies >1 publications with OASL and Proteinuria Fibrosis Antibodies >1 publications with OASL and Fibrosis Weight Loss Antibodies >1 publications with OASL and Weight Loss Organs/Tissues associated with OASL recombinant protein Organ/Tissue Name Pubmed Publications Blood Antibodies >17 publications with OASL and Blood Liver Antibodies >7 publications with OASL and Liver Lung Antibodies >5 publications with OASL and Lung Bone Antibodies >2 publications with OASL and Bone Brain Antibodies >2 publications with OASL and Brain Muscle Antibodies >1 publications with OASL and Muscle Bone Marrow Antibodies >1 publications with OASL and Bone Marrow Prostate Antibodies >1 publications with OASL and Prostate Thyroid Antibodies >1 publications with OASL and Thyroid Intestine Antibodies >1 publications with OASL and Intestine TOP © 2006-24 MyBioSource.com. 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