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RPL35A recombinant protein :: 60S ribosomal protein L35a Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS955821
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $675 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $825 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $910 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,020 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,040 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,065 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,510 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,545 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,630 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,025 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

60S ribosomal protein L35a (RPL35A), Recombinant Protein

 Also Known As   

Recombinant Human 60S ribosomal protein L35a

 Product Synonym Names    Cell growth-inhibiting gene 33 protein
 Product Gene Name   

RPL35A recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-110aa; Full Length
 Sequence    MSGRLWSKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFRS NLPAKAIGHR IRVMLYPSRI
 OMIM    180468
 3D Structure    ModBase 3D Structure for P18077
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of RPL35A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for RPL35A recombinant protein

   Required for the proliferation and viability of hatopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
 Product Categories/Family for RPL35A recombinant protein    Epigenetics and Nuclear Signaling
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 SDS-PAGE of RPL35A recombinant protein    RPL35A recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for RPL35A. It may not necessarily be applicable to this product.
 NCBI GI #    16117791
 NCBI GeneID    6165
 NCBI Accession #    NP_000987.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000996.2 [Other Products]
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 UniProt Primary Accession #    P18077 [Other Products]
 UniProt Secondary Accession #    Q08ES9; Q9BVN7 [Other Products]
 UniProt Related Accession #    P18077 [Other Products]
 Molecular Weight    28.5kD
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 NCBI Official Full Name    60S ribosomal protein L35a
 NCBI Official Synonym Full Names    ribosomal protein L35a
 NCBI Official Symbol    RPL35A [Similar Products]
 NCBI Official Synonym Symbols   
DBA5; L35A
[Similar Products]
 NCBI Protein Information    60S ribosomal protein L35a
 UniProt Protein Name    60S ribosomal protein L35a
 UniProt Synonym Protein Names   
Cell growth-inhibiting gene 33 protein
 Protein Family    60S ribosomal protein
 UniProt Gene Name    RPL35A [Similar Products]
 UniProt Entry Name    RL35A_HUMAN
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 NCBI Summary for RPL35A    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L35AE family of ribosomal proteins. It is located in the cytoplasm. The rat protein has been shown to bind to both initiator and elongator tRNAs, and thus, it is located at the P site, or P and A sites, of the ribosome. Although this gene was originally mapped to chromosome 18, it has been established that it is located at 3q29-qter. Alternative splicing results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Oct 2015]
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 UniProt Comments for RPL35A    RPL35A: Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site. Defects in RPL35A are the cause of Diamond-Blackfan anemia type 5 (DBA5). DBA5 is a form of Diamond- Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Belongs to the ribosomal protein L35Ae family.

Protein type: Translation; RNA-binding; Ribosomal

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: cytosol; membrane; mitochondrion

Molecular Function: structural constituent of ribosome; tRNA binding

Biological Process: cellular protein metabolic process; gene expression; mRNA catabolic process, nonsense-mediated decay; ribosomal large subunit biogenesis and assembly; rRNA processing; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription

Disease: Diamond-blackfan Anemia 5
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Product References and Citations for RPL35A recombinant protein

   cDNA encoding the human homologue of rat ribosomal protein L35a.Herzog H., Hfferer L., Schneider R., Schweiger M.Nucleic Acids Res. 18:4600-4600(1990) Identification of a cell growth-inhibiting gene.Kim J.W., Kim H.K.
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 Research Articles on RPL35A    1. Data show 1 proband with an RPL5 deletion, 1 patient with an RPL35A deletion, 3 with RPS17 deletions, and 1 with an RPS19 deletion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RPL35A recombinant proteinDiseases associated with RPL35A recombinant protein
 Reference Product  PubMed Publications
 RPL5 recombinant protein  >21 publications with RPL35A and RPL5
 RPL13 recombinant protein  >2 publications with RPL35A and RPL13
 RPL14 recombinant protein  >2 publications with RPL35A and RPL14
 RPL30 recombinant protein  >2 publications with RPL35A and RPL30
 RPL36 recombinant protein  >2 publications with RPL35A and RPL36
 RPL32 recombinant protein  >1 publications with RPL35A and RPL32
 RPL38 recombinant protein  >1 publications with RPL35A and RPL38
 RPL31 recombinant protein  >1 publications with RPL35A and RPL31
 RPL18A recombinant protein  >1 publications with RPL35A and RPL18A
 RPL29 recombinant protein  >1 publications with RPL35A and RPL29
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >6 publications with RPL35A and Congenital Abnormalities
 Diamond-Blackfan Anemia 5 Antibodies  >5 publications with RPL35A and Diamond-Blackfan Anemia 5
 Death Antibodies  >3 publications with RPL35A and Death
 Chromosome Aberrations Antibodies  >3 publications with RPL35A and Chromosome Aberrations
 Aneuploidy Antibodies  >1 publications with RPL35A and Aneuploidy
 Atrophy Antibodies  >1 publications with RPL35A and Atrophy
Organs/Tissues associated with RPL35A recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with RPL35A and Blood
 Bone Antibodies  >12 publications with RPL35A and Bone
 Bone Marrow Antibodies  >11 publications with RPL35A and Bone Marrow
 Heart Antibodies  >5 publications with RPL35A and Heart
 Brain Antibodies  >4 publications with RPL35A and Brain
 Spleen Antibodies  >1 publications with RPL35A and Spleen
 Ear Antibodies  >1 publications with RPL35A and Ear
 Vascular Antibodies  >1 publications with RPL35A and Vascular
 Liver Antibodies  >1 publications with RPL35A and Liver
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