NP_001076091.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
57,494 Da
NCBI Official Full Name
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
NCBI Protein Information
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
UniProt Protein Name
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
UniProt Synonym Protein Names
7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase
UniProt Synonym Gene Names
UniProt Entry Name
CP8B1_RABIT
UniProt Comments for CYP8B1
Involved in bile acid synthesis and is responsible for the conversion of 7-alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
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Pathways associated with CYP8B1 recombinant protein
Diseases associated with CYP8B1 recombinant protein
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