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ADAM9 recombinant protein :: A Disintegrin And Metalloprotease 9 (ADAM9) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2009998 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $270 +1 FREE 8GB USB
0.1 mg  /  $420 +1 FREE 8GB USB
0.2 mg  /  $515 +1 FREE 8GB USB
0.5 mg  /  $990 +1 FREE 8GB USB
1 mg  /  $1,475 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloprotease 9 (ADAM9), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant A Disintegrin And Metalloprotease 9 (ADAM9)

 Product Gene Name   

ADAM9 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2009998 Technical Datasheet    Technical Datasheet PDF
 Chromosome Location    Chromosome: 8; NC_000008.10 (38854505..38962780). Location: 8p11.22
 OMIM    602713
 3D Structure    ModBase 3D Structure for Q13443
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 Host    E Coli
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 Purity/Purification    > 97%
 Concentration    Original Concentration: 200 ug/mL (lot specific)
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 Organism Species    Homo sapiens (Human)
 Source    Prokaryotic expression
 Residues    Pro440~Gly680
 Tags    N-terminal His Tag
 Subcellular Location    Membrane
 Traits    Freeze-dried powder
 Buffer    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
 Predicted isoelectric point    7.0
 Predicted Molecular Mass    27.3kDa
 Accurate Molecular Mass    27kDa as determined by SDS-PAGE reducing conditions
 USAGE    Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8C for one month.
Aliquot and store at -80C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of ADAM9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for ADAM9 recombinant protein   

Positive Control; Immunogen; SDS-PAGE; WB.

(May be suitable for use in other assays to be determined by the end user.)

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 SDS-PAGE of ADAM9 recombinant protein    ADAM9 recombinant protein SDS-PAGE image
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 Sequence of ADAM9 recombinant protein    ADAM9 recombinant protein Sequence image
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NCBI/Uniprot data below describe general gene information for ADAM9. It may not necessarily be applicable to this product.
 NCBI GI #    4501915
 NCBI GeneID    8754
 NCBI Accession #    NP_003807.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003816.2 [Other Products]
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 UniProt Primary Accession #    Q13443 [Other Products]
 UniProt Secondary Accession #    Q10718; Q8NFM6; B7ZLN7 [Other Products]
 UniProt Related Accession #    Q13443 [Other Products]
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 NCBI Official Full Name    disintegrin and metalloproteinase domain-containing protein 9
 NCBI Official Synonym Full Names    ADAM metallopeptidase domain 9
 NCBI Official Symbol    ADAM9 [Similar Products]
 NCBI Official Synonym Symbols   
MCMP; MDC9; CORD9; Mltng
[Similar Products]
 NCBI Protein Information    disintegrin and metalloproteinase domain-containing protein 9; cone rod dystrophy 9; myeloma cell metalloproteinase; cellular disintegrin-related protein; ADAM metallopeptidase domain 9 (meltrin gamma); metalloprotease/disintegrin/cysteine-rich protein 9
 UniProt Protein Name    Disintegrin and metalloproteinase domain-containing protein 9
 UniProt Synonym Protein Names   
Cellular disintegrin-related protein; Meltrin-gamma; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    ADAM9 [Similar Products]
 UniProt Synonym Gene Names    KIAA0021; MCMP; MDC9; MLTNG; ADAM 9 [Similar Products]
 UniProt Entry Name    ADAM9_HUMAN
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 NCBI Summary for ADAM9    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]
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 UniProt Comments for ADAM9    ADAM9: Probable zinc protease. May mediate cell-cell or cell- matrix interactions. Isoform 2 displays alpha-secretase activity for APP. Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Protease; Membrane protein, integral; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 8p11.22

Cellular Component: extracellular space; focal adhesion; cell surface; basolateral plasma membrane; cytoplasm; integral to membrane

Molecular Function: integrin binding; collagen binding; protein binding; protein kinase C binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity; laminin binding; SH3 domain binding

Biological Process: integrin-mediated signaling pathway; positive regulation of keratinocyte migration; extracellular matrix organization and biogenesis; activation of MAPKK activity; cell-matrix adhesion; response to glucocorticoid stimulus; membrane protein ectodomain proteolysis; positive regulation of cell adhesion mediated by integrin; positive regulation of membrane protein ectodomain proteolysis; response to manganese ion; keratinocyte differentiation; extracellular matrix disassembly; collagen catabolic process; PMA-inducible membrane protein ectodomain proteolysis; response to hydrogen peroxide; monocyte activation; positive regulation of protein secretion; transforming growth factor beta receptor signaling pathway; cell-cell adhesion mediated by integrin; cell adhesion mediated by integrin; cell adhesion; response to calcium ion

Disease: Cone-rod Dystrophy 9
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 Research Articles on ADAM9    1. ADAM9 is an important molecule in the processes of invasion and metastasis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADAM9 recombinant proteinPathways associated with ADAM9 recombinant protein
 Reference Product  PubMed Publications
 TGFB1 recombinant protein  >2 publications with ADAM9 and TGFB1
 DIF recombinant protein  >1 publications with ADAM9 and DIF
 SH3GL2 recombinant protein  >1 publications with ADAM9 and SH3GL2
 SNX9 recombinant protein  >1 publications with ADAM9 and SNX9
 MAD2L2 recombinant protein  >1 publications with ADAM9 and MAD2L2
 Products by Pathway  Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with ADAM9 recombinant proteinOrgans/Tissues associated with ADAM9 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >75 publications with ADAM9 and Neoplasms
 Necrosis Antibodies  >40 publications with ADAM9 and Necrosis
 Neoplasm Metastasis Antibodies  >13 publications with ADAM9 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >11 publications with ADAM9 and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >11 publications with ADAM9 and Prostatic Neoplasms
 Cardiovascular Diseases Antibodies  >9 publications with ADAM9 and Cardiovascular Diseases
 Liver Diseases Antibodies  >9 publications with ADAM9 and Liver Diseases
 Inflammation Antibodies  >8 publications with ADAM9 and Inflammation
 Liver Neoplasms Antibodies  >8 publications with ADAM9 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >7 publications with ADAM9 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >27 publications with ADAM9 and Muscle
 Blood Antibodies  >23 publications with ADAM9 and Blood
 Brain Antibodies  >21 publications with ADAM9 and Brain
 Vascular Antibodies  >18 publications with ADAM9 and Vascular
 Lung Antibodies  >14 publications with ADAM9 and Lung
 Prostate Antibodies  >14 publications with ADAM9 and Prostate
 Bone Antibodies  >13 publications with ADAM9 and Bone
 Liver Antibodies  >11 publications with ADAM9 and Liver
 Embryonic Tissue Antibodies  >10 publications with ADAM9 and Embryonic Tissue
 Skin Antibodies  >10 publications with ADAM9 and Skin
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