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ADAMTS12 recombinant protein :: A Disintegrin And Metalloproteinase With Thrombospondin 12 (ADAMTS12) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2011347 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $145 +1 FREE 8GB USB
0.05 mg  /  $280 +1 FREE 8GB USB
0.1 mg  /  $435 +1 FREE 8GB USB
0.2 mg  /  $535 +1 FREE 8GB USB
0.5 mg  /  $1,035 +1 FREE 8GB USB
1 mg  /  $1,540 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloproteinase With Thrombospondin 12 (ADAMTS12), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 12 (ADAMTS12)

 Product Gene Name   

ADAMTS12 recombinant protein

[Similar Products]
 Matching Pairs    Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 12 (MBS2028647)
Antigen: A Disintegrin And Metalloproteinase With Thrombospondin 12 (ADAMTS12) (MBS2011347)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG S-SPA YWIVGNWSKC STTCGLGAYW RSVECSSGVD ADCTTIQRPD PAKKCHLRPC AGWRVGNWSK CSRNCSGGFK IREVQCMDSL DHHRSLRPFH CQFLAGAPPP LSMSCNLEPC GEWQVEPWSQ CSRSCGGGVQ ERGVSCPGGL CDWTKRPATT VPCNRHLCCH WATGNWELCN TSCGGGSQKR TIHCIPSENS TTEDQDQCLC DHQVKPPEFQ TCNQQACR
 Chromosome Location    Chromosome: 15; NC_000081.6 (11064790..11349235). Location: 15 A1; 15
 3D Structure    ModBase 3D Structure for Q811B3
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Mus musculus (Mouse)
 Expression System    Prokaryotic expression
 Residues    Ser1318-Arg1538 (Accession # Q811B3) with N-terminal His-Tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of ADAMTS12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ADAMTS12 recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for ADAMTS12 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of ADAMTS12 recombinant protein    ADAMTS12 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for ADAMTS12. It may not necessarily be applicable to this product.
 NCBI GI #    153945812
 NCBI GeneID    239337
 NCBI Accession #    NP_780710.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_175501.2 [Other Products]
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 UniProt Primary Accession #    Q811B3 [Other Products]
 UniProt Secondary Accession #    Q8BK92; Q8BKY1; E9QKD6 [Other Products]
 UniProt Related Accession #    Q811B3 [Other Products]
 Molecular Weight    25.7kDa
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 12
 NCBI Official Synonym Full Names    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
 NCBI Official Symbol    Adamts12 [Similar Products]
 NCBI Official Synonym Symbols   
AI605170; ADAMTS-12
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS12; ADAM-TS 12; metalloprotease disintegrin 12; a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 12; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 12
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    Adamts12 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 12; ADAM-TS12; ADAMTS-12 [Similar Products]
 UniProt Entry Name    ATS12_MOUSE
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 UniProt Comments for ADAMTS12    ADAMTS12: Metalloprotease that may play a role in the degradation of COMP. Cleaves also alpha-2 macroglobulin and aggregan. Has anti-tumorigenic properties. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; EC 3.4.24.-; Protease; Secreted; Secreted, signal peptide

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular region

Molecular Function: peptidase activity; metallopeptidase activity; hydrolase activity; zinc ion binding; metal ion binding; metalloendopeptidase activity

Biological Process: cell migration; proteolysis involved in cellular protein catabolic process; cell-matrix adhesion; negative regulation of chondrocyte differentiation; regulation of inflammatory response; proteoglycan catabolic process; proteolysis
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 Research Articles on ADAMTS12    1. ADAMTS-12 is implicated in the inflammatory response by modulating normal neutrophil apoptosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with ADAMTS12 recombinant proteinOrgans/Tissues associated with ADAMTS12 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >5 publications with ADAMTS12 and Disease Models, Animal
 Necrosis Antibodies  >3 publications with ADAMTS12 and Necrosis
 Inflammation Antibodies  >3 publications with ADAMTS12 and Inflammation
 Cardiovascular Diseases Antibodies  >2 publications with ADAMTS12 and Cardiovascular Diseases
 Mental Disorders Antibodies  >1 publications with ADAMTS12 and Mental Disorders
 Kidney Diseases Antibodies  >1 publications with ADAMTS12 and Kidney Diseases
 Brain Diseases Antibodies  >1 publications with ADAMTS12 and Brain Diseases
 Lung Neoplasms Antibodies  >1 publications with ADAMTS12 and Lung Neoplasms
 Arteriosclerosis Antibodies  >1 publications with ADAMTS12 and Arteriosclerosis
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with ADAMTS12 and Lung
 Connective Tissue Antibodies  >3 publications with ADAMTS12 and Connective Tissue
 Ovary Antibodies  >1 publications with ADAMTS12 and Ovary
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