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ADAMTS7 recombinant protein :: A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2010788 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $175 +1 FREE 8GB USB
0.05 mg  /  $360 +1 FREE 8GB USB
0.1 mg  /  $560 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7)

 Product Gene Name   

ADAMTS7 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF-VQ RRLVKCVNTQ TGLPEEDSDQ CGHEAWPESS RPCGTEDCEP VEPPRCERDR LSFGFCETLR LLGRCQLPTI RTQCCRSCSP PSHGAPSRGH QRVARR
 Chromosome Location    Chromosome: 15; NC_000015.9 (79051545..79103805, complement). Location: 15q24.2
 OMIM    605009
 3D Structure    ModBase 3D Structure for Q9UKP4
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and preservative.
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 Residues    Val1589~Arg1686
 Tags Information    N-terminal His-Tag
 Endotoxin Level    <1.0EU per 1ug(determined by the LAL method).
 Predicted isoelectric point    7.6
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of ADAMTS7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for ADAMTS7 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of ADAMTS7 recombinant protein    ADAMTS7 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for ADAMTS7. It may not necessarily be applicable to this product.
 NCBI GI #    38683827
 NCBI GeneID    11173
 NCBI Accession #    NP_055087.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_014272.3 [Other Products]
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 UniProt Primary Accession #    Q9UKP4 [Other Products]
 UniProt Secondary Accession #    Q14F51; Q6P7J9 [Other Products]
 UniProt Related Accession #    Q9UKP4 [Other Products]
 Molecular Weight    12.6kDa
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 7 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif, 7
 NCBI Official Symbol    ADAMTS7 [Similar Products]
 NCBI Official Synonym Symbols   
ADAM-TS7; ADAMTS-7; ADAM-TS 7
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 7; COMPase; a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 7
 UniProt Synonym Protein Names   
COMPase
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    ADAMTS7 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 7; ADAM-TS7; ADAMTS-7 [Similar Products]
 UniProt Entry Name    ATS7_HUMAN
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 NCBI Summary for ADAMTS7    The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAMTS7    ADAMTS7: Metalloprotease that may play a role in the degradation of COMP.

Protein type: Cell surface; Secreted, signal peptide; Secreted; EC 3.4.24.-; Protease; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: proteinaceous extracellular matrix; cell surface; endoplasmic reticulum lumen

Molecular Function: protein binding; zinc ion binding; metallopeptidase activity; metalloendopeptidase activity

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; proteolysis involved in cellular protein catabolic process; negative regulation of chondrocyte differentiation; post-translational protein modification
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 Research Articles on ADAMTS7    1. There was a reduction in the amount of cleaved ADAMTS7 prodomain in media conditioned by VSMCs of the G/G genotype.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADAMTS7 recombinant proteinDiseases associated with ADAMTS7 recombinant protein
 Reference Product  PubMed Publications
 PTHLH recombinant protein  >1 publications with ADAMTS7 and PTHLH
 FURIN recombinant protein  >1 publications with ADAMTS7 and FURIN
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >9 publications with ADAMTS7 and Cardiovascular Diseases
 Coronary Artery Disease Antibodies  >8 publications with ADAMTS7 and Coronary Artery Disease
 Arteriosclerosis Antibodies  >7 publications with ADAMTS7 and Arteriosclerosis
 Necrosis Antibodies  >5 publications with ADAMTS7 and Necrosis
 Inflammation Antibodies  >3 publications with ADAMTS7 and Inflammation
 Thrombosis Antibodies  >1 publications with ADAMTS7 and Thrombosis
 Hypertension Antibodies  >1 publications with ADAMTS7 and Hypertension
 Urinary Bladder Neoplasms Antibodies  >1 publications with ADAMTS7 and Urinary Bladder Neoplasms
 Congenital Abnormalities Antibodies  >1 publications with ADAMTS7 and Congenital Abnormalities
 Hyperplasia Antibodies  >1 publications with ADAMTS7 and Hyperplasia
Organs/Tissues associated with ADAMTS7 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >3 publications with ADAMTS7 and Connective Tissue
 Heart Antibodies  >3 publications with ADAMTS7 and Heart
 Kidney Antibodies  >1 publications with ADAMTS7 and Kidney
 Eye Antibodies  >1 publications with ADAMTS7 and Eye
 Embryonic Tissue Antibodies  >1 publications with ADAMTS7 and Embryonic Tissue
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