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Add To Compare List Mutyh recombinant protein :: A/G-specific adenine DNA glycosylase (Mutyh) Recombinant Protein Catalog # MBS1385839 Unit / Price 0.02 mg (E-Coli) / $1,095 +1 FREE 8GB USB 0.02 mg (Yeast) / $1,145 +1 FREE 8GB USB 0.1 mg (E-Coli) / $1,275 +1 FREE 8GB USB 0.1 mg (Yeast) / $1,345 +1 FREE 8GB USB 0.02 mg (Baculovirus) / $1,385 +1 FREE 8GB USB 0.02 mg (Mammalian-Cell) / $1,650 +2 FREE 8GB USB 0.1 mg (Baculovirus) / $1,990 +2 FREE 8GB USB 1 mg (E-Coli) / $2,295 +2 FREE 8GB USB 0.1 mg (Mammalian-Cell) / $2,585 +3 FREE 8GB USB 1 mg (Yeast) / $2,665 +3 FREE 8GB USB 1 mg (Baculovirus) / $3,845 +4 FREE 8GB USB 0.5 mg (Mammalian-Cell) / $6,265 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name A/G-specific adenine DNA glycosylase (Mutyh), Recombinant Protein Full Product Name Recombinant Mouse A/G-specific adenine DNA glycosylase (Mutyh) Product Gene Name Mutyh recombinant protein[Similar Products] Product Synonym Gene Name Mutyh[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Positions 1-515, Full length protein Sequence MKKLQASVRS HKKQPANHKR RRTRALSSSQ AKPSSLDGLA KQKREELLQA SVSPYHLFSD VADVTAFRSN LLSWYDQEKR DLPWRNLAKE EANSDRRAYA VWVSEVMLQQ TQVATVIDYY TRWMQKWPKL QDLASASLEE VNQLWSGLGY YSRGRRLQEG ARKVVEELGG HMPRTAETLQ QLLPGVGRYT AGAIASIAFD QVTGVVDGNV LRVLCRVRAI GADPTSTLVS HHLWNLAQQL VDPARPGDFN QAAMELGATV CTPQRPLCSH CPVQSLCRAY QRVQRGQLSA LPGRPDIEEC ALNTRQCQLC LTSSSPWDPS MGVANFPRKA SRRPPREEYS ATCVVEQPGA IGGPLVLLVQ RPDSGLLAGL WEFPSVTLEP SEQHQHKALL QELQRWCGPL PAIRLQHLGE VIHIFSHIKL TYQVYSLALD QAPASTAPPG ARWLTWEEFC NAAVSTAMKK VFRMYEDHRQ GTRKGSKRSQ VCPPSSRKKP SLGQQVLDTF FQRHIPTDKP NSTTQ 3D Structure ModBase 3D Structure for Q99P21 Host E Coli or Yeast or Baculovirus or Mammalian Cell Purity/Purification Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific) Form/Format Lyophilized or liquid (Format to be determined during the manufacturing process) Tag Information This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information. Sterility Sterile filter available upon request. Endotoxin Low endotoxin available upon request. Species Mouse Preparation and Storage Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of Mutyh recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Mutyh recombinant protein This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. NCBI/Uniprot data below describe general gene information for Mutyh. It may not necessarily be applicable to this product. NCBI GI # 227330623 NCBI GeneID 70603 NCBI Accession # NP_001153053.1 [Other Products] NCBI GenBank Nucleotide # NM_001159581.1 [Other Products] UniProt Primary Accession # Q99P21 [Other Products] UniProt Secondary Accession # A2AGE3[Other Products] UniProt Related Accession # Q99P21[Other Products] Molecular Weight 57,723 Da TOP NCBI Official Full Name adenine DNA glycosylase isoform a NCBI Official Synonym Full Names mutY DNA glycosylase NCBI Official Symbol Mutyh [Similar Products] NCBI Official Synonym Symbols Myh; Mutyha; Mutyhb; Mutyhc; Mutyhbeta; Mutyhalpha; 5730495A01Rik [Similar Products] NCBI Protein Information adenine DNA glycosylase UniProt Protein Name Adenine DNA glycosylase UniProt Synonym Protein Names MutY homolog; mMYH UniProt Gene Name Mutyh [Similar Products] UniProt Synonym Gene Names Myh; mMYH [Similar Products] TOP TOP UniProt Comments for Mutyh Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities. Research Articles on Mutyh 1. results suggested that MYH, which interacts with TRADD, inhibits TNF-alpha necroptotic signaling. Therefore, MYH inactivation is essential for necroptosis via the downregulation of caspase-8. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with Mutyh recombinant protein Reference Product PubMed Publications Ogg1 recombinant protein >57 publications with Mutyh and Ogg1 Msh6 recombinant protein >19 publications with Mutyh and Msh6 Apex1 recombinant protein >14 publications with Mutyh and Apex1 Pcna recombinant protein >7 publications with Mutyh and Pcna Rad1 recombinant protein >5 publications with Mutyh and Rad1 Hus1 recombinant protein >4 publications with Mutyh and Hus1 Toe1 recombinant protein >2 publications with Mutyh and Toe1 Apex2 recombinant protein >2 publications with Mutyh and Apex2 Hus1b recombinant protein >1 publications with Mutyh and Hus1b Neil3 recombinant protein >1 publications with Mutyh and Neil3 Pathways associated with Mutyh recombinant protein Products by Pathway Pathway Diagram Base Excision Repair Pathway antibodies Base Excision Repair Pathway Diagram Base Excision Repair Pathway antibodies Base Excision Repair Pathway Diagram Base Excision Repair Pathway antibodies Base Excision Repair Pathway Diagram Base-Excision Repair, AP Site Formation Pathway antibodies Base-Excision Repair, AP Site Formation Pathway Diagram Base-free Sugar-phosphate Removal Via The Single-nucleotide Replacement Pathway antibodies Base-free Sugar-phosphate Removal Via The Single-nucleotide Replacement Pathway Diagram Cleavage Of The Damaged Purine Pathway antibodies Cleavage Of The Damaged Purine Pathway Diagram DNA Repair Pathway antibodies DNA Repair Pathway Diagram Depurination Pathway antibodies Depurination Pathway Diagram Displacement Of DNA Glycosylase By APE1 Pathway antibodies Displacement Of DNA Glycosylase By APE1 Pathway Diagram Recognition And Association Of DNA Glycosylase With Site Containing An Affected Purine Pathway antibodies Recognition And Association Of DNA Glycosylase With Site Containing An Affected Purine Pathway Diagram Diseases associated with Mutyh recombinant protein Disease Name Pubmed Publications Neoplasms Antibodies >165 publications with Mutyh and Neoplasms Gastrointestinal Diseases Antibodies >141 publications with Mutyh and Gastrointestinal Diseases Adenoma Antibodies >85 publications with Mutyh and Adenoma Adenomatous Polyposis Coli Antibodies >77 publications with Mutyh and Adenomatous Polyposis Coli Carcinoma Antibodies >35 publications with Mutyh and Carcinoma FAMILIAL ADENOMATOUS POLYPOSIS, 2 Antibodies >32 publications with Mutyh and FAMILIAL ADENOMATOUS POLYPOSIS, 2 Adenocarcinoma Antibodies >12 publications with Mutyh and Adenocarcinoma Lung Neoplasms Antibodies >11 publications with Mutyh and Lung Neoplasms Nervous System Diseases Antibodies >8 publications with Mutyh and Nervous System Diseases Skin Neoplasms Antibodies >6 publications with Mutyh and Skin Neoplasms Organs/Tissues associated with Mutyh recombinant protein Organ/Tissue Name Pubmed Publications Intestine Antibodies >8 publications with Mutyh and Intestine Brain Antibodies >8 publications with Mutyh and Brain Thyroid Antibodies >7 publications with Mutyh and Thyroid Liver Antibodies >6 publications with Mutyh and Liver Bone Antibodies >1 publications with Mutyh and Bone Thymus Antibodies >1 publications with Mutyh and Thymus Embryonic Tissue Antibodies >1 publications with Mutyh and Embryonic Tissue TOP © 2006-24 MyBioSource.com. 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