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Mutyh recombinant protein :: A/G-specific adenine DNA glycosylase (Mutyh) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1415521 Mutyh recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $940 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,140 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,260 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,370 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,385 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,390 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,445 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,550 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,970 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,070 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,095 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,355 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,725 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A/G-specific adenine DNA glycosylase (Mutyh), Recombinant Protein

 Also Known As   

Recombinant Rat A/G-specific adenine DNA glycosylase (Mutyh)

 Product Gene Name   

Mutyh recombinant protein

[Similar Products]
 Product Synonym Gene Name    Mutyh [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-516aa, full length protein
 Sequence    MKKLRASVRS HKKQPANHKR RGKCALSSSQ AKPSGLDGLA KQKREELLKT PVSPYHLFSD IADVTAFRRN LLSWYDQEKR DLPWRKRVKE ETNLDRRAYA VWVSEVMLQQ TQVATVIDYY TRWMQKWPTL QDLASASLEE VNQLWSGLGY YSRGRRLQEG ARKVVEELGG HVPRTAETLQ QLLPGVGRYT AGAIASIAFD QVTGVVDGNV IRVLCRVRAI GADPTSSFVS HHLWDLAQQL VDPARPGDFN QAAMELGATV CTPQRPLCNH CPVQSLCRAH QRVGQGRLSA LPGSPDIEEC ALNTRQCQLC LPSTNPWDPN MGVVNFPRKA SRRPPREEYS ATCVVEQPGA TGGPLILLVQ RPNSGLLAGL WEFPSVTLEP SGQHQHKALL QELQHWSAPL PTTPLQHLGE VIHVFSHIKL TYQVYSLALE GQTPASTTLP GARWLTWEEF RNAAVSTAMK KVFRVYEEHR RGTCKGSKRP QVCTPSSRKK PSRGQQVLDR FFQRHIPTHK PNSTTQ
 3D Structure    ModBase 3D Structure for Q8R5G2
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Mutyh recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Mutyh recombinant protein

   This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for Mutyh. It may not necessarily be applicable to this product.
 NCBI GI #    18959262
 NCBI GeneID    170841
 NCBI Accession #    NP_579850.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_133316.1 [Other Products]
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 UniProt Primary Accession #    Q8R5G2 [Other Products]
 UniProt Related Accession #    Q8R5G2 [Other Products]
 Molecular Weight    57,919 Da
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 NCBI Official Full Name    adenine DNA glycosylase
 NCBI Official Synonym Full Names    mutY DNA glycosylase
 NCBI Official Symbol    Mutyh [Similar Products]
 NCBI Official Synonym Symbols   
Myh
[Similar Products]
 NCBI Protein Information    adenine DNA glycosylase
 UniProt Protein Name    Adenine DNA glycosylase
 UniProt Synonym Protein Names   
MutY homolog; rMYH
 UniProt Gene Name    Mutyh [Similar Products]
 UniProt Synonym Gene Names    Myh; rMYH [Similar Products]
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 NCBI Summary for Mutyh    an DNA repair enzyme that excises adenine residues misincorporated opposite the oxidized base [RGD, Feb 2006]
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 UniProt Comments for Mutyh    Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.
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 Research Articles on Mutyh    1. respiratory hypoxia leads to increased expression of MYH in the rat brain
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Mutyh recombinant proteinDiseases associated with Mutyh recombinant protein
 Products by Pathway  Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base-Excision Repair, AP Site Formation Pathway antibodies  Base-Excision Repair, AP Site Formation Pathway Diagram
 Base-free Sugar-phosphate Removal Via The Single-nucleotide Replacement Pathway antibodies  Base-free Sugar-phosphate Removal Via The Single-nucleotide Replacement Pathway Diagram
 Cleavage Of The Damaged Purine Pathway antibodies  Cleavage Of The Damaged Purine Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 Depurination Pathway antibodies  Depurination Pathway Diagram
 Displacement Of DNA Glycosylase By APE1 Pathway antibodies  Displacement Of DNA Glycosylase By APE1 Pathway Diagram
 Recognition And Association Of DNA Glycosylase With Site Containing An Affected Purine Pathway antibodies  Recognition And Association Of DNA Glycosylase With Site Containing An Affected Purine Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >165 publications with Mutyh and Neoplasms
 Gastrointestinal Diseases Antibodies  >141 publications with Mutyh and Gastrointestinal Diseases
 Adenoma Antibodies  >85 publications with Mutyh and Adenoma
 Adenomatous Polyposis Coli Antibodies  >77 publications with Mutyh and Adenomatous Polyposis Coli
 Carcinoma Antibodies  >36 publications with Mutyh and Carcinoma
 FAMILIAL ADENOMATOUS POLYPOSIS, 2 Antibodies  >32 publications with Mutyh and FAMILIAL ADENOMATOUS POLYPOSIS, 2
 Adenocarcinoma Antibodies  >12 publications with Mutyh and Adenocarcinoma
 Lung Neoplasms Antibodies  >11 publications with Mutyh and Lung Neoplasms
 Nervous System Diseases Antibodies  >8 publications with Mutyh and Nervous System Diseases
 Skin Neoplasms Antibodies  >6 publications with Mutyh and Skin Neoplasms
Organs/Tissues associated with Mutyh recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with Mutyh and Brain
 Liver Antibodies  >6 publications with Mutyh and Liver
 Prostate Antibodies  >2 publications with Mutyh and Prostate
 Kidney Antibodies  >1 publications with Mutyh and Kidney
 Pancreas Antibodies  >1 publications with Mutyh and Pancreas
 Thymus Antibodies  >1 publications with Mutyh and Thymus
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