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Adamts1 recombinant protein :: A disintegrin and metalloproteinase with thrombospondin motifs 1 (Adamts1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS950471 Adamts1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $1,145 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,295 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,545 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,545 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,600 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,645 +2 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,705 +2 FREE 8GB USB
0.5 mg (Yeast)  /  $1,810 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,325 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,345 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,430 +3 FREE 8GB USB
1 mg (Yeast)  /  $2,735 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $3,070 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A disintegrin and metalloproteinase with thrombospondin motifs 1 (Adamts1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 1 (Adamts1)

 Product Gene Name   

Adamts1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    254-968aa, Full Length of Mature Protein
 Sequence    FVSSPRYVET MLVADQSMAD FHGSGLKHYL LTLFSVAARF YKHPSIRNSI SLVVVKILVI YEEQKGPEVT SNAALTLRNF CSWQKQHNSP SDRDPEHYDT AILFTRQDLC GSHTCDTLGM ADVGTVCDPS RSCSVIEDDG LQAAFTTAHE LGHVFNMPHD DAKHCASLNG VSGDSHLMAS MLSSLDHSQP WSPCSAYMVT SFLDNGHGEC LMDKPQNPIK LPSDLPGTLY DANRQCQFTF GEESKHCPDA ASTCTTLWCT GTSGGLLVCQ TKHFPWADGT SCGEGKWCVS GKCVNKTDMK HFATPVHGSW GPWGPWGDCS RTCGGGVQYT MRECDNPVPK NGGKYCEGKR VRYRSCNIED CPDNNGKTFR EEQCEAHNEF SKASFGNEPT VEWTPKYAGV SPKDRCKLTC EAKGIGYFFV LQPKVVDGTP CSPDSTSVCV QGQCVKAGCD RIIDSKKKFD KCGVCGGNGS TCKKMSGIVT STRPGYHDIV TIPAGATNIE VKHRNQRGSR NNGSFLAIRA ADGTYILNGN FTLSTLEQDL TYKGTVLRYS GSSAALERIR SFSPLKEPLT IQVLMVGHAL RPKIKFTYFM KKKTESFNAI PTFSEWVIEE WGECSKTCGS GWQRRVVQCR DINGHPASEC AKEVKPASTR PCADLPCPHW QVGDWSPCSK TCGKGYKKRT LKCVSHDGGV LSNESCDPLK KPKHYIDFCT LTQCS
 3D Structure    ModBase 3D Structure for P97857
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Adamts1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Adamts1 recombinant protein

   This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
NCBI/Uniprot data below describe general gene information for Adamts1. It may not necessarily be applicable to this product.
 NCBI GI #    157951646
 NCBI GeneID    11504
 NCBI Accession #    NP_033751.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_009621.5 [Other Products]
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 UniProt Primary Accession #    P97857 [Other Products]
 UniProt Secondary Accession #    O54768; E9QMN9 [Other Products]
 UniProt Related Accession #    P97857 [Other Products]
 Molecular Weight    105,801 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 1 preproprotein
 NCBI Official Synonym Full Names    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
 NCBI Official Symbol    Adamts1 [Similar Products]
 NCBI Official Synonym Symbols   
C3-C5; METH1; ADAMTS; METH-1; ADAM-TS1; ADAMTS-1
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 1
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 1
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    Adamts1 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 1; ADAM-TS1; ADAMTS-1 [Similar Products]
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 NCBI Summary for Adamts1    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family and preproprotein that is proteolytically processed to generate a mature protein product. This secreted protein product plays an important role in ovulation, likely through its cleavage of the extracellular matrix component versican. The encoded protein may enhance tumorigenesis in a mouse model of breast cancer. Homozygous knockout mice for this gene exhibit enhanced perinatal lethality, impaired growth and adipose tissue development, and impaired ovulation in females. [provided by RefSeq, Oct 2015]
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 UniProt Comments for Adamts1    Cleaves aggrecan, a cartilage proteoglycan, at the '1691-Glu-|-Leu-1692' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity (). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture ().
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 Research Articles on Adamts1    1. Data show that NOTCH1 is a target of ADAMTS1 metalloproteinase activity, which reduces Notch signaling, leading to increased satellite cell activation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Adamts1 recombinant proteinPathways associated with Adamts1 recombinant protein
 Reference Product  PubMed Publications
 Timp3 recombinant protein  >10 publications with Adamts1 and Timp3
 Vegfa recombinant protein  >9 publications with Adamts1 and Vegfa
 Vcan recombinant protein  >7 publications with Adamts1 and Vcan
 Mmp13 recombinant protein  >6 publications with Adamts1 and Mmp13
 Fgf2 recombinant protein  >4 publications with Adamts1 and Fgf2
 Adam17 recombinant protein  >3 publications with Adamts1 and Adam17
 Timp1 recombinant protein  >3 publications with Adamts1 and Timp1
 Sdc4 recombinant protein  >3 publications with Adamts1 and Sdc4
 Vegfc recombinant protein  >2 publications with Adamts1 and Vegfc
 Fbln1 recombinant protein  >1 publications with Adamts1 and Fbln1
 Products by Pathway  Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
Diseases associated with Adamts1 recombinant proteinOrgans/Tissues associated with Adamts1 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >32 publications with Adamts1 and Cardiovascular Diseases
 Inflammation Antibodies  >25 publications with Adamts1 and Inflammation
 Necrosis Antibodies  >19 publications with Adamts1 and Necrosis
 Neoplasms, Experimental Antibodies  >16 publications with Adamts1 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >15 publications with Adamts1 and Breast Neoplasms
 Fibrosis Antibodies  >14 publications with Adamts1 and Fibrosis
 Kidney Diseases Antibodies  >11 publications with Adamts1 and Kidney Diseases
 Brain Diseases Antibodies  >10 publications with Adamts1 and Brain Diseases
 Liver Diseases Antibodies  >9 publications with Adamts1 and Liver Diseases
 Lung Diseases Antibodies  >9 publications with Adamts1 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >61 publications with Adamts1 and Blood
 Ovary Antibodies  >42 publications with Adamts1 and Ovary
 Muscle Antibodies  >30 publications with Adamts1 and Muscle
 Bone Antibodies  >29 publications with Adamts1 and Bone
 Connective Tissue Antibodies  >26 publications with Adamts1 and Connective Tissue
 Kidney Antibodies  >24 publications with Adamts1 and Kidney
 Brain Antibodies  >22 publications with Adamts1 and Brain
 Embryonic Tissue Antibodies  >19 publications with Adamts1 and Embryonic Tissue
 Lung Antibodies  >16 publications with Adamts1 and Lung
 Prostate Antibodies  >10 publications with Adamts1 and Prostate
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