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Adamts12 recombinant protein :: A disintegrin and metalloproteinase with thrombospondin motifs 12 (Adamts12), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1329749 Adamts12 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,035 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,035 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,265 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,265 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,555 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,555 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,015 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,015 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,050 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,835 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A disintegrin and metalloproteinase with thrombospondin motifs 12 (Adamts12), partial, Recombinant Protein

 Also Known As   

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12 (Adamts12), partial

 Product Synonym Names    A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS 12; ADAM-TS12; ADAMTS-12; EC=3.4.24.-
 Product Gene Name   

Adamts12 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    210-460, Partial, include the Cysteine switch motif and Peptidase M12B domain.
 Sequence    PICGLKDSLD NSVKQELQRE KWERKTLRSR SLSRRSISKE RWVETLVVAD TKTVEYHGSE NVESYILTIM NMVTGLFHSP SIGNLVHIVV VRLILLEEEE QGLKIVHHAE KTLSSFCKWQ KSINPKSDLN PVHHDVAVLI TRKDICAGVN RPCETLGLSQ LSGMCQPHRS CNINEDSGLP LAFTIAHELG HSFGIQHDGK ENDCEPVGRH PYIMSQQIQY DPTPLTWSKC SKEYITRFLD RGRGFCLDDI P
 3D Structure    ModBase 3D Structure for Q811B3
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Adamts12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Adamts12. It may not necessarily be applicable to this product.
 NCBI GI #    153945812
 NCBI GeneID    239337
 NCBI Accession #    NP_780710.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_175501.2 [Other Products]
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 UniProt Primary Accession #    Q811B3 [Other Products]
 UniProt Secondary Accession #    Q8BK92; Q8BKY1; E9QKD6 [Other Products]
 UniProt Related Accession #    Q811B3 [Other Products]
 Molecular Weight    18,843 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 12
 NCBI Official Synonym Full Names    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
 NCBI Official Symbol    Adamts12 [Similar Products]
 NCBI Official Synonym Symbols   
AI605170; ADAMTS-12
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS12; ADAM-TS 12; metalloprotease disintegrin 12; a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 12; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 12
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    Adamts12 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 12; ADAM-TS12; ADAMTS-12 [Similar Products]
 UniProt Entry Name    ATS12_MOUSE
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 UniProt Comments for Adamts12    ADAMTS12: Metalloprotease that may play a role in the degradation of COMP. Cleaves also alpha-2 macroglobulin and aggregan. Has anti-tumorigenic properties. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Protease; Secreted, signal peptide; Motility/polarity/chemotaxis; EC 3.4.24.-

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular region

Molecular Function: peptidase activity; zinc ion binding; metallopeptidase activity; hydrolase activity; metal ion binding; metalloendopeptidase activity

Biological Process: cell migration; proteolysis involved in cellular protein catabolic process; cell-matrix adhesion; regulation of inflammatory response; negative regulation of chondrocyte differentiation; proteoglycan catabolic process; proteolysis
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 Research Articles on Adamts12    1. ADAMTS-12 is implicated in the inflammatory response by modulating normal neutrophil apoptosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Adamts12 recombinant proteinOrgans/Tissues associated with Adamts12 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >5 publications with Adamts12 and Disease Models, Animal
 Inflammation Antibodies  >3 publications with Adamts12 and Inflammation
 Necrosis Antibodies  >3 publications with Adamts12 and Necrosis
 Cardiovascular Diseases Antibodies  >2 publications with Adamts12 and Cardiovascular Diseases
 Schizophrenia Antibodies  >1 publications with Adamts12 and Schizophrenia
 Mental Disorders Antibodies  >1 publications with Adamts12 and Mental Disorders
 Lung Neoplasms Antibodies  >1 publications with Adamts12 and Lung Neoplasms
 Kidney Diseases Antibodies  >1 publications with Adamts12 and Kidney Diseases
 Brain Diseases Antibodies  >1 publications with Adamts12 and Brain Diseases
 Arteriosclerosis Antibodies  >1 publications with Adamts12 and Arteriosclerosis
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with Adamts12 and Lung
 Connective Tissue Antibodies  >3 publications with Adamts12 and Connective Tissue
 Ovary Antibodies  >1 publications with Adamts12 and Ovary
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