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Adamts12 recombinant protein :: A disintegrin and metalloproteinase with thrombospondin motifs 12 (Adamts12) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1329749 Adamts12 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,035 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,035 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,265 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,265 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,555 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,555 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,015 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,015 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,050 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,835 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A disintegrin and metalloproteinase with thrombospondin motifs 12 (Adamts12), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12 (Adamts12) , partial

 Product Gene Name   

Adamts12 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Adamts12 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    210-460, Partial, include the Cysteine switch motif and Peptidase M12B domain.
 Sequence    PICGLKDSLD NSVKQELQRE KWERKTLRSR SLSRRSISKE RWVETLVVAD TKTVEYHGSE NVESYILTIM NMVTGLFHSP SIGNLVHIVV VRLILLEEEE QGLKIVHHAE KTLSSFCKWQ KSINPKSDLN PVHHDVAVLI TRKDICAGVN RPCETLGLSQ LSGMCQPHRS CNINEDSGLP LAFTIAHELG HSFGIQHDGK ENDCEPVGRH PYIMSQQIQY DPTPLTWSKC SKEYITRFLD RGRGFCLDDI P
 3D Structure    ModBase 3D Structure for Q811B3
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Adamts12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Adamts12 recombinant protein

   This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.
NCBI/Uniprot data below describe general gene information for Adamts12. It may not necessarily be applicable to this product.
 NCBI GI #    153945812
 NCBI GeneID    239337
 NCBI Accession #    NP_780710.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_175501.3 [Other Products]
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 UniProt Primary Accession #    Q811B3 [Other Products]
 UniProt Secondary Accession #    Q8BK92; Q8BKY1; E9QKD6 [Other Products]
 UniProt Related Accession #    Q811B3 [Other Products]
 Molecular Weight    18,843 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 12 preproprotein
 NCBI Official Synonym Full Names    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
 NCBI Official Symbol    Adamts12 [Similar Products]
 NCBI Official Synonym Symbols   
AI605170; ADAMTS-12
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 12
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 12
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    Adamts12 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 12; ADAM-TS12; ADAMTS-12 [Similar Products]
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 NCBI Summary for Adamts12    This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active protease. Mice lacking the encoded protein exhibit increased angiogenic response and tumor invasion in different models of angiogenesis and, severe inflammation and delayed recovery when subjected to experimental conditions that induce colitis, endotoxic sepsis and pancreatitis. [provided by RefSeq, Jul 2016]
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 UniProt Comments for Adamts12    Metalloprotease that plays a role in the degradation of COMP (). Cleaves also alpha-2 macroglobulin and aggregan. Has anti-tumorigenic properties ().
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 Research Articles on Adamts12    1. ADAMTS-12 is a multifaced metalloproteinase in arthritis and inflammation [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Adamts12 recombinant proteinDiseases associated with Adamts12 recombinant protein
 Reference Product  PubMed Publications
 Comp recombinant protein  >6 publications with Adamts12 and Comp
 Furin recombinant protein  >2 publications with Adamts12 and Furin
 Grn recombinant protein  >1 publications with Adamts12 and Grn
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >5 publications with Adamts12 and Disease Models, Animal
 Inflammation Antibodies  >4 publications with Adamts12 and Inflammation
 Necrosis Antibodies  >4 publications with Adamts12 and Necrosis
 Mental Disorders Antibodies  >2 publications with Adamts12 and Mental Disorders
 Atherosclerosis Antibodies  >1 publications with Adamts12 and Atherosclerosis
 Arteriosclerosis Antibodies  >1 publications with Adamts12 and Arteriosclerosis
 Brain Diseases Antibodies  >1 publications with Adamts12 and Brain Diseases
 Breast Neoplasms Antibodies  >1 publications with Adamts12 and Breast Neoplasms
 Lung Neoplasms Antibodies  >1 publications with Adamts12 and Lung Neoplasms
 Kidney Diseases Antibodies  >1 publications with Adamts12 and Kidney Diseases
Organs/Tissues associated with Adamts12 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >5 publications with Adamts12 and Connective Tissue
 Lung Antibodies  >3 publications with Adamts12 and Lung
 Ovary Antibodies  >1 publications with Adamts12 and Ovary
 Embryonic Tissue Antibodies  >1 publications with Adamts12 and Embryonic Tissue
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