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Adamts18 recombinant protein :: A disintegrin and metalloproteinase with thrombospondin motifs 18 (Adamts18), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1335874 Adamts18 recombinant protein
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A disintegrin and metalloproteinase with thrombospondin motifs 18 (Adamts18), partial, Recombinant Protein

 Also Known As   

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 18 (Adamts18), partial

 Product Synonym Names    A disintegrin and metalloproteinase with thrombospondin motifs 18; ADAM-TS 18; ADAM-TS18; ADAMTS-18; EC=3.4.24.-
 Product Gene Name   

Adamts18 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q4VC17
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Adamts18 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Adamts18. It may not necessarily be applicable to this product.
 NCBI GI #    121583653
 NCBI GeneID    208936
 NCBI Accession #    NP_766054.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_172466.2 [Other Products]
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 UniProt Primary Accession #    Q4VC17 [Other Products]
 UniProt Secondary Accession #    Q8BZD1; E9QNK0 [Other Products]
 UniProt Related Accession #    Q4VC17 [Other Products]
 Molecular Weight    135,244 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 18
 NCBI Official Synonym Full Names    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
 NCBI Official Symbol    Adamts18 [Similar Products]
 NCBI Official Synonym Symbols   
ADAMTS21; 9630038L21; E130314N14Rik
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 18; ADAM-TS18; ADAMTS-18; ADAM-TS 18; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 18
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    Adamts18 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 18; ADAM-TS18; ADAMTS-18 [Similar Products]
 UniProt Entry Name    ATS18_MOUSE
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 UniProt Comments for Adamts18    ADAMTS18: Defects in ADAMTS18 are the cause of Knobloch syndrome type 2 (KNO2). A developmental disorder primarily characterized by typical eye abnormalities, including high myopia, cataracts, dislocated lens, vitreoretinal degeneration, and retinal detachment, with occipital skull defects, which can range from occipital encephalocele to occult cutis aplasia. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Protease; Secreted, signal peptide; Secreted; EC 3.4.24.-

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular region

Molecular Function: peptidase activity; zinc ion binding; metallopeptidase activity; hydrolase activity; metalloendopeptidase activity; metal ion binding

Biological Process: eye development; proteolysis
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 Research Articles on Adamts18    1. these data demonstrate a thrombin cleavage site and confirm a short form of ADAMTS-18 presents in vivo.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Adamts18 recombinant proteinOrgans/Tissues associated with Adamts18 recombinant protein
 Disease Name  Pubmed Publications
 Eye Abnormalities Antibodies  >3 publications with Adamts18 and Eye Abnormalities
 Nervous System Malformations Antibodies  >3 publications with Adamts18 and Nervous System Malformations
 Neoplasm Metastasis Antibodies  >2 publications with Adamts18 and Neoplasm Metastasis
 Atrophy Antibodies  >2 publications with Adamts18 and Atrophy
 Craniofacial Abnormalities Antibodies  >1 publications with Adamts18 and Craniofacial Abnormalities
 Musculoskeletal Abnormalities Antibodies  >1 publications with Adamts18 and Musculoskeletal Abnormalities
 Inflammation Antibodies  >1 publications with Adamts18 and Inflammation
 Brain Diseases Antibodies  >1 publications with Adamts18 and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >5 publications with Adamts18 and Eye
 Lung Antibodies  >3 publications with Adamts18 and Lung
 Brain Antibodies  >2 publications with Adamts18 and Brain
 Embryonic Tissue Antibodies  >1 publications with Adamts18 and Embryonic Tissue
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